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Rhoa ras homolog family member A [ Rattus norvegicus (Norway rat) ]

Gene ID: 117273, updated on 26-May-2016
Official Symbol
Rhoaprovided by RGD
Official Full Name
ras homolog family member Aprovided by RGD
Primary source
RGD:619921
See related
Ensembl:ENSRNOG00000050519
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Arha; Arha2
Orthologs
Location:
chromosome: 8
Exon count:
7
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (117082440..117116244)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (116431244..116464932)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene aminomethyltransferase Neighboring gene T-cell leukemia translocation altered Neighboring gene glutathione peroxidase 1 Neighboring gene ubiquitin specific peptidase 4 Neighboring gene hypothetical LOC498675

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Adherens junction, organism-specific biosystem (from KEGG)
    Adherens junction, organism-specific biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
  • Adherens junction, conserved biosystem (from KEGG)
    Adherens junction, conserved biosystemCell-cell adherens junctions (AJs), the most common type of intercellular adhesions, are important for maintaining tissue architecture and cell polarity and can limit cell movement and proliferation....
  • Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem
    Alpha6-Beta4 Integrin Signaling Pathway
  • Axon guidance, organism-specific biosystem (from KEGG)
    Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • Axon guidance, conserved biosystem (from KEGG)
    Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
  • B Cell Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
    B Cell Receptor Signaling Pathway, organism-specific biosystemThe B cell receptor includes membrane ???? heavy chain molecules bound to a light chain and an Ig alpha (CD79A)/Ig beta (CD79B) heterodimer. Activation of the B cell receptor involves phosphorylation...
  • Bacterial invasion of epithelial cells, organism-specific biosystem (from KEGG)
    Bacterial invasion of epithelial cells, organism-specific biosystemMany pathogenic bacteria can invade phagocytic and non-phagocytic cells and colonize them intracellularly, then become disseminated to other cells. Invasive bacteria induce their own uptake by non-ph...
  • Bacterial invasion of epithelial cells, conserved biosystem (from KEGG)
    Bacterial invasion of epithelial cells, conserved biosystemMany pathogenic bacteria can invade phagocytic and non-phagocytic cells and colonize them intracellularly, then become disseminated to other cells. Invasive bacteria induce their own uptake by non-ph...
  • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
    Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
  • Chemokine signaling pathway, conserved biosystem (from KEGG)
    Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
  • Colorectal cancer, organism-specific biosystem (from KEGG)
    Colorectal cancer, organism-specific biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
  • Colorectal cancer, conserved biosystem (from KEGG)
    Colorectal cancer, conserved biosystemColorectal cancer (CRC) is the second largest cause of cancer-related deaths in Western countries. CRC arises from the colorectal epithelium as a result of the accumulation of genetic alterations in ...
  • Endocytosis, organism-specific biosystem (from KEGG)
    Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Endocytosis, conserved biosystem (from KEGG)
    Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Focal adhesion, organism-specific biosystem (from KEGG)
    Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • Focal adhesion, conserved biosystem (from KEGG)
    Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
  • G Protein Signaling Pathways, organism-specific biosystem (from WikiPathways)
    G Protein Signaling Pathways, organism-specific biosystemG proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They...
  • G13 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    G13 Signaling Pathway, organism-specific biosystemThe G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cell...
  • Leukocyte transendothelial migration, organism-specific biosystem (from KEGG)
    Leukocyte transendothelial migration, organism-specific biosystemLeukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (C...
  • Leukocyte transendothelial migration, conserved biosystem (from KEGG)
    Leukocyte transendothelial migration, conserved biosystemLeukocyte migaration from the blood into tissues is vital for immune surveillance and inflammation. During this diapedesis of leukocytes, the leukocytes bind to endothelial cell adhesion molecules (C...
  • MicroRNAs in cancer, organism-specific biosystem (from KEGG)
    MicroRNAs in cancer, organism-specific biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • MicroRNAs in cancer, conserved biosystem (from KEGG)
    MicroRNAs in cancer, conserved biosystemMicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, which controls gene expression post-transcriptionally either via the degradation of target mRNAs or...
  • Neurotrophin signaling pathway, organism-specific biosystem (from KEGG)
    Neurotrophin signaling pathway, organism-specific biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
  • Neurotrophin signaling pathway, conserved biosystem (from KEGG)
    Neurotrophin signaling pathway, conserved biosystemNeurotrophins are a family of trophic factors involved in differentiation and survival of neural cells. The neurotrophin family consists of nerve growth factor (NGF), brain derived neurotrophic facto...
  • Oxytocin signaling pathway, organism-specific biosystem (from KEGG)
    Oxytocin signaling pathway, organism-specific biosystemOxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. It exerts a wide variety of central and ...
  • Oxytocin signaling pathway, conserved biosystem (from KEGG)
    Oxytocin signaling pathway, conserved biosystemOxytocin (OT) is a nonapeptide synthesized by the magno-cellular neurons located in the supraoptic (SON) and paraventricular (PVN) nuclei of the hypothalamus. It exerts a wide variety of central and ...
  • Pancreatic secretion, organism-specific biosystem (from KEGG)
    Pancreatic secretion, organism-specific biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Pancreatic secretion, conserved biosystem (from KEGG)
    Pancreatic secretion, conserved biosystemThe pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two parts, the acinar and duct cells. The primary functions of pancreatic acinar cells are to synthesiz...
  • Pathways in cancer, organism-specific biosystem (from KEGG)
    Pathways in cancer, organism-specific biosystem
    Pathways in cancer
  • Pertussis, organism-specific biosystem (from KEGG)
    Pertussis, organism-specific biosystemPertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory whe...
  • Pertussis, conserved biosystem (from KEGG)
    Pertussis, conserved biosystemPertussis, also known as whooping cough, is an acute respiratory infectious disease caused by a bacteria called Bordetella Pertussis. The characteristic symptoms are paroxysmal cough, inspiratory whe...
  • Phospholipase D signaling pathway, organism-specific biosystem (from KEGG)
    Phospholipase D signaling pathway, organism-specific biosystemPhospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second messenger phosphatidic acid (PA), which is involved in fundamental cellular processes, including membra...
  • Phospholipase D signaling pathway, conserved biosystem (from KEGG)
    Phospholipase D signaling pathway, conserved biosystemPhospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second messenger phosphatidic acid (PA), which is involved in fundamental cellular processes, including membra...
  • Platelet activation, organism-specific biosystem (from KEGG)
    Platelet activation, organism-specific biosystemPlatelets play a key and beneficial role for primary hemostasis on the disruption of the integrity of vessel wall. Platelet adhesion and activation at sites of vascular wall injury is initiated by ad...
  • Proteoglycans in cancer, organism-specific biosystem (from KEGG)
    Proteoglycans in cancer, organism-specific biosystemMany proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that contribute to biology of various types of cancer including proliferation, adhesion, angiogenesis a...
  • Proteoglycans in cancer, conserved biosystem (from KEGG)
    Proteoglycans in cancer, conserved biosystemMany proteoglycans (PGs) in the tumor microenvironment have been shown to be key macromolecules that contribute to biology of various types of cancer including proliferation, adhesion, angiogenesis a...
  • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
    Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Rap1 signaling pathway, conserved biosystem (from KEGG)
    Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Ras signaling pathway, organism-specific biosystem (from KEGG)
    Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
  • Regulation of Actin Cytoskeleton, organism-specific biosystem (from WikiPathways)
    Regulation of Actin Cytoskeleton, organism-specific biosystem
    Regulation of Actin Cytoskeleton
  • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
    Regulation of actin cytoskeleton, organism-specific biosystem
    Regulation of actin cytoskeleton
  • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
    Regulation of actin cytoskeleton, conserved biosystem
    Regulation of actin cytoskeleton
  • Sphingolipid signaling pathway, organism-specific biosystem (from KEGG)
    Sphingolipid signaling pathway, organism-specific biosystemSphingomyelin (SM) and its metabolic products are now known to have second messenger functions in a variety of cellular signaling pathways. Particularly, the sphingolipid metabolites, ceramide (Cer) ...
  • Sphingolipid signaling pathway, conserved biosystem (from KEGG)
    Sphingolipid signaling pathway, conserved biosystemSphingomyelin (SM) and its metabolic products are now known to have second messenger functions in a variety of cellular signaling pathways. Particularly, the sphingolipid metabolites, ceramide (Cer) ...
  • Spinal Cord Injury, organism-specific biosystem (from WikiPathways)
    Spinal Cord Injury, organism-specific biosystemThis pathway provides an overview of cell types, therapeutic targets, drugs, new proposed targets and pathways implicated in spinal cord injury. Spinal cord injury is a complex multistep process that...
  • T cell receptor signaling pathway, organism-specific biosystem (from KEGG)
    T cell receptor signaling pathway, organism-specific biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...
  • T cell receptor signaling pathway, conserved biosystem (from KEGG)
    T cell receptor signaling pathway, conserved biosystemActivation of T lymphocytes is a key event for an efficient response of the immune system. It requires the involvement of the T-cell receptor (TCR) as well as costimulatory molecules such as CD28. En...
  • TGF-beta signaling pathway, organism-specific biosystem (from KEGG)
    TGF-beta signaling pathway, organism-specific biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
  • TGF-beta signaling pathway, conserved biosystem (from KEGG)
    TGF-beta signaling pathway, conserved biosystemThe transforming growth factor-beta (TGF-beta) family members, which include TGF-betas, activins and bone morphogenetic proteins (BMPs), are structurally related secreted cytokines found in species r...
  • Tight junction, organism-specific biosystem (from KEGG)
    Tight junction, organism-specific biosystemEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of ma...
  • Tight junction, conserved biosystem (from KEGG)
    Tight junction, conserved biosystemEpithelial tight junctions (TJs) are composed of at least three types of transmembrane protein -occludin, claudin and junctional adhesion molecules (JAMs)- and a cytoplasmic 'plaque' consisting of ma...
  • Tuberculosis, organism-specific biosystem (from KEGG)
    Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Tuberculosis, conserved biosystem (from KEGG)
    Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
  • Vascular smooth muscle contraction, organism-specific biosystem (from KEGG)
    Vascular smooth muscle contraction, organism-specific biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
  • Vascular smooth muscle contraction, conserved biosystem (from KEGG)
    Vascular smooth muscle contraction, conserved biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
  • Viral carcinogenesis, organism-specific biosystem (from KEGG)
    Viral carcinogenesis, organism-specific biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • Viral carcinogenesis, conserved biosystem (from KEGG)
    Viral carcinogenesis, conserved biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
  • Wnt Signaling Pathway, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • Wnt Signaling Pathway NetPath, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway NetPath, organism-specific biosystemWnt family of proteins are a large family of cysteine-rich secreted glycoproteins that regulate cell-cell interactions. They bind to members of the Frizzled family of 7 transmembrane receptors. Bindi...
  • Wnt Signaling Pathway and Pluripotency, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway and Pluripotency, organism-specific biosystemThis pathway was adapted from several resources and is designed to provide a theoretical frame-work for examining Wnt signaling and interacting components in the context of embryonic stem-cell pluri...
  • Wnt signaling pathway, organism-specific biosystem (from KEGG)
    Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • Wnt signaling pathway, conserved biosystem (from KEGG)
    Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • cAMP signaling pathway, organism-specific biosystem (from KEGG)
    cAMP signaling pathway, organism-specific biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • cAMP signaling pathway, conserved biosystem (from KEGG)
    cAMP signaling pathway, conserved biosystemcAMP is one of the most common and universal second messengers, and its formation is promoted by adenylyl cyclase (AC) activation after ligation of G protein-coupled receptors (GPCRs) by ligands incl...
  • cGMP-PKG signaling pathway, organism-specific biosystem (from KEGG)
    cGMP-PKG signaling pathway, organism-specific biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
  • cGMP-PKG signaling pathway, conserved biosystem (from KEGG)
    cGMP-PKG signaling pathway, conserved biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC72339

Gene Ontology Provided by RGD

Function Evidence Code Pubs
GDP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding ISO
Inferred from Sequence Orthology
more info
 
GTP binding TAS
Traceable Author Statement
more info
PubMed 
GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
GTPase activity ISO
Inferred from Sequence Orthology
more info
 
GTPase activity NAS
Non-traceable Author Statement
more info
PubMed 
GTPase activity TAS
Traceable Author Statement
more info
PubMed 
Rho GDP-dissociation inhibitor binding IPI
Inferred from Physical Interaction
more info
PubMed 
myosin binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
GTP metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
Rho protein signal transduction ISO
Inferred from Sequence Orthology
more info
 
Rho protein signal transduction ISS
Inferred from Sequence or Structural Similarity
more info
 
Roundabout signaling pathway ISO
Inferred from Sequence Orthology
more info
 
Roundabout signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
actin cytoskeleton organization TAS
Traceable Author Statement
more info
PubMed 
actin cytoskeleton reorganization ISO
Inferred from Sequence Orthology
more info
 
actin cytoskeleton reorganization ISS
Inferred from Sequence or Structural Similarity
more info
 
alpha-beta T cell lineage commitment IEA
Inferred from Electronic Annotation
more info
 
alpha-beta T cell lineage commitment ISO
Inferred from Sequence Orthology
more info
 
androgen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
androgen receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure ISO
Inferred from Sequence Orthology
more info
 
apical junction assembly ISO
Inferred from Sequence Orthology
more info
 
apical junction assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
apolipoprotein A-I-mediated signaling pathway ISO
Inferred from Sequence Orthology
more info
 
beta selection IEA
Inferred from Electronic Annotation
more info
 
beta selection ISO
Inferred from Sequence Orthology
more info
 
cell adhesion ISO
Inferred from Sequence Orthology
more info
 
cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cell migration ISO
Inferred from Sequence Orthology
more info
 
cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
cell morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 
cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
 
cellular response to progesterone stimulus NAS
Non-traceable Author Statement
more info
PubMed 
cerebral cortex cell migration IEA
Inferred from Electronic Annotation
more info
 
cerebral cortex cell migration ISO
Inferred from Sequence Orthology
more info
 
cleavage furrow formation ISO
Inferred from Sequence Orthology
more info
 
cleavage furrow formation ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
endothelial cell migration ISO
Inferred from Sequence Orthology
more info
 
endothelial tube lumen extension ISO
Inferred from Sequence Orthology
more info
 
forebrain radial glial cell differentiation IEA
Inferred from Electronic Annotation
more info
 
forebrain radial glial cell differentiation ISO
Inferred from Sequence Orthology
more info
 
mitotic cleavage furrow formation ISO
Inferred from Sequence Orthology
more info
 
mitotic cleavage furrow formation ISS
Inferred from Sequence or Structural Similarity
more info
 
mitotic spindle assembly ISO
Inferred from Sequence Orthology
more info
 
negative chemotaxis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of I-kappaB kinase/NF-kappaB signaling IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell death IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of cell migration involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of intracellular steroid hormone receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of intracellular steroid hormone receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of oxidative phosphorylation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of oxidative phosphorylation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of reactive oxygen species biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of reactive oxygen species biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
neuron projection morphogenesis IEP
Inferred from Expression Pattern
more info
PubMed 
odontogenesis IEA
Inferred from Electronic Annotation
more info
 
ossification involved in bone maturation IEA
Inferred from Electronic Annotation
more info
 
ossification involved in bone maturation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of actin filament polymerization IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of alpha-beta T cell differentiation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of alpha-beta T cell differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell adhesion IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of cell growth IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of cell growth IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cell migration IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cytokinesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cytokinesis ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of lipase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of neuron differentiation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of podosome assembly IEA
Inferred from Electronic Annotation
more info
 
positive regulation of podosome assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein serine/threonine kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of smooth muscle contraction IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of translation IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of vascular smooth muscle contraction ISO
Inferred from Sequence Orthology
more info
 
positive regulation of vasoconstriction IEP
Inferred from Expression Pattern
more info
PubMed 
regulation of actin cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
regulation of actin polymerization or depolymerization IEP
Inferred from Expression Pattern
more info
PubMed 
regulation of calcium ion transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
regulation of cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of dendrite development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
regulation of microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
regulation of neural precursor cell proliferation IEA
Inferred from Electronic Annotation
more info
 
regulation of neural precursor cell proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
regulation of osteoblast proliferation IEA
Inferred from Electronic Annotation
more info
 
regulation of osteoblast proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of systemic arterial blood pressure by endothelin ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
response to amino acid IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IDA
Inferred from Direct Assay
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to ethanol IEP
Inferred from Expression Pattern
more info
PubMed 
response to glucocorticoid IEP
Inferred from Expression Pattern
more info
PubMed 
response to glucose IEP
Inferred from Expression Pattern
more info
PubMed 
response to hypoxia IEP
Inferred from Expression Pattern
more info
PubMed 
response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
skeletal muscle satellite cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
skeletal muscle tissue development IEA
Inferred from Electronic Annotation
more info
 
skeletal muscle tissue development ISO
Inferred from Sequence Orthology
more info
 
stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
stress fiber assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
stress-activated protein kinase signaling cascade IMP
Inferred from Mutant Phenotype
more info
PubMed 
substantia nigra development ISO
Inferred from Sequence Orthology
more info
 
trabecula morphogenesis IEA
Inferred from Electronic Annotation
more info
 
trabecula morphogenesis ISO
Inferred from Sequence Orthology
more info
 
wound healing, spreading of cells ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
apical junction complex ISO
Inferred from Sequence Orthology
more info
 
apical junction complex ISS
Inferred from Sequence or Structural Similarity
more info
 
axon IDA
Inferred from Direct Assay
more info
PubMed 
cell cortex ISO
Inferred from Sequence Orthology
more info
 
cell cortex ISS
Inferred from Sequence or Structural Similarity
more info
 
cell periphery ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with cleavage furrow ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with cleavage furrow ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of cytoplasmic side of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
focal adhesion ISO
Inferred from Sequence Orthology
more info
 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
lamellipodium ISS
Inferred from Sequence or Structural Similarity
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
midbody IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
ruffle membrane IEA
Inferred from Electronic Annotation
more info
 
ruffle membrane ISO
Inferred from Sequence Orthology
more info
 
vesicle ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
transforming protein RhoA
Names
plysia ras-related homolog A2
ras homolog gene family, member A

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_057132.3NP_476473.1  transforming protein RhoA precursor

    See identical proteins and their annotated locations for NP_476473.1

    Status: PROVISIONAL

    Source sequence(s)
    AY026068
    UniProtKB/Swiss-Prot
    P61589
    Related
    ENSRNOP00000066672, ENSRNOT00000071664
    Conserved Domains (2) summary
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC
    pfam00071
    Location:7180
    Ras; Ras family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    117082440..117116244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006243699.1XP_006243761.1  

    See identical proteins and their annotated locations for XP_006243761.1

    UniProtKB/Swiss-Prot
    P61589
    Conserved Domains (2) summary
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC
    pfam00071
    Location:7180
    Ras; Ras family
  2. XM_006243700.1XP_006243762.1  

    See identical proteins and their annotated locations for XP_006243762.1

    UniProtKB/Swiss-Prot
    P61589
    Conserved Domains (2) summary
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC
    pfam00071
    Location:7180
    Ras; Ras family
  3. XM_006243701.1XP_006243763.1  

    See identical proteins and their annotated locations for XP_006243763.1

    UniProtKB/Swiss-Prot
    P61589
    Conserved Domains (2) summary
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC
    pfam00071
    Location:7180
    Ras; Ras family

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    108319010..108327586
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)