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Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 [ Mus musculus (house mouse) ]

Gene ID: 11668, updated on 28-May-2016
Official Symbol
Aldh1a1provided by MGI
Official Full Name
aldehyde dehydrogenase family 1, subfamily A1provided by MGI
Primary source
MGI:MGI:1353450
See related
Ensembl:ENSMUSG00000053279 Vega:OTTMUSG00000021238
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
E1; Ahd2; Ahd-2; Aldh1; Raldh1; Aldh1a2
Location:
19 B; 19 13.91 cM
Exon count:
13
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 19 NC_000085.6 (20601982..20643462)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (20676472..20717952)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA E030003E18 gene Neighboring gene RIKEN cDNA C730002L08 gene Neighboring gene glutathione S-transferase kappa 1 Neighboring gene aldehyde dehydrogenase family 1, subfamily A7 Neighboring gene transmembrane channel-like gene family 1 Neighboring gene predicted gene, 32750

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
3-chloroallyl aldehyde dehydrogenase activity IDA
Inferred from Direct Assay
more info
PubMed 
aldehyde dehydrogenase (NAD) activity ISO
Inferred from Sequence Orthology
more info
 
benzaldehyde dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
benzaldehyde dehydrogenase (NAD+) activity ISO
Inferred from Sequence Orthology
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 
retinal dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
9-cis-retinoic acid biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
9-cis-retinoic acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
embryonic eye morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
metabolic process IEA
Inferred from Electronic Annotation
more info
 
optic cup morphogenesis involved in camera-type eye development IGI
Inferred from Genetic Interaction
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
protein homotetramerization ISO
Inferred from Sequence Orthology
more info
 
response to drug IDA
Inferred from Direct Assay
more info
PubMed 
response to ethanol ISO
Inferred from Sequence Orthology
more info
 
response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
retinoic acid biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
retinoic acid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
retinoic acid metabolic process IGI
Inferred from Genetic Interaction
more info
PubMed 
retinoic acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
retinol metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
retinal dehydrogenase 1
Names
ALDH-E1
ALHDII
RALDH 1
alcohol dehydrogenase family 1, subfamily A1
alcohol dehydrogenase family 1, subfamily A2
aldehyde dehydrogenase 1, liver cytosolic (class 1)
aldehyde dehydrogenase family 1 member A1
aldehyde dehydrogenase, cytosolic
NP_038495.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013467.3NP_038495.2  retinal dehydrogenase 1

    See identical proteins and their annotated locations for NP_038495.2

    Status: PROVISIONAL

    Source sequence(s)
    AC152162, AC167167
    Consensus CDS
    CCDS29695.1
    UniProtKB/Swiss-Prot
    P24549
    Related
    ENSMUSP00000084918, OTTMUSP00000023466, ENSMUST00000087638, OTTMUST00000050305
    Conserved Domains (1) summary
    cd07141
    Location:15495
    ALDH_F1AB_F2_RALDH1; NAD+-dependent retinal dehydrogenase 1, ALDH families 1A, 1B, and 2-like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p3 C57BL/6J

    Range
    20601982..20643462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000041.1 Alternate Mm_Celera

    Range
    21323202..21366435
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)