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Akap4 A kinase (PRKA) anchor protein 4 [ Mus musculus (house mouse) ]

Gene ID: 11643, updated on 8-May-2016
Official Symbol
Akap4provided by MGI
Official Full Name
A kinase (PRKA) anchor protein 4provided by MGI
Primary source
MGI:MGI:102794
See related
Ensembl:ENSMUSG00000050089 Vega:OTTMUSG00000016457
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p82; Fsc1; PRKA4; AKAP-4; AKAP82; mAKAP82
Orthologs
Location:
X A1.1; X 3.17 cM
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X NC_000086.7 (7067515..7078609)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X NC_000086.6 (6644645..6655735)

Chromosome X - NC_000086.7Genomic Context describing neighboring genes Neighboring gene diacylglycerol kinase kappa Neighboring gene cyclin B3 Neighboring gene ribosomal protein L23a pseudogene Neighboring gene chloride channel, voltage-sensitive 5 Neighboring gene microRNA 500

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • G Protein Signaling Pathways, organism-specific biosystem (from WikiPathways)
    G Protein Signaling Pathways, organism-specific biosystemG proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase A binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell projection organization IEA
Inferred from Electronic Annotation
more info
 
establishment of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
motile cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein kinase A signaling IBA
Inferred from Biological aspect of Ancestor
more info
 
sperm motility IMP
Inferred from Mutant Phenotype
more info
PubMed 
sperm motility ISO
Inferred from Sequence Orthology
more info
 
transmembrane receptor protein serine/threonine kinase signaling pathway IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
Z disc IDA
Inferred from Direct Assay
more info
PubMed 
cell projection IEA
Inferred from Electronic Annotation
more info
 
cilium IDA
Inferred from Direct Assay
more info
PubMed 
motile cilium IDA
Inferred from Direct Assay
more info
PubMed 
motile cilium ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
sperm fibrous sheath IDA
Inferred from Direct Assay
more info
PubMed 
sperm principal piece IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
A-kinase anchor protein 4
Names
A-kinase anchor protein 82 kDa
major sperm fibrous sheath protein
protein kinase A-anchoring protein 4

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042542.2NP_001036007.1  A-kinase anchor protein 4 isoform b

    See identical proteins and their annotated locations for NP_001036007.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon compared to variant 1. The encoded isoform (b) has a shorter N-terminus compared to isoform a.
    Source sequence(s)
    AL808124
    Consensus CDS
    CCDS40839.1
    UniProtKB/Swiss-Prot
    Q60662
    Related
    ENSMUSP00000111417, ENSMUST00000115751
    Conserved Domains (1) summary
    cl14906
    Location:5840
    AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)
  2. NM_009651.4NP_033781.2  A-kinase anchor protein 4 isoform a

    See identical proteins and their annotated locations for NP_033781.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AL808124, BC130271
    Consensus CDS
    CCDS40838.1
    UniProtKB/Swiss-Prot
    Q60662
    UniProtKB/TrEMBL
    A1L3T6
    Related
    ENSMUSP00000050962, OTTMUSP00000017697, ENSMUST00000057101, OTTMUST00000039653
    Conserved Domains (1) summary
    cl14906
    Location:14849
    AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000086.7 Reference GRCm38.p3 C57BL/6J

    Range
    7067515..7078609
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000042.1 Alternate Mm_Celera

    Range
    4385111..4395990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)