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DNTTIP1 deoxynucleotidyltransferase, terminal, interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 116092, updated on 26-May-2016
Official Symbol
DNTTIP1provided by HGNC
Official Full Name
deoxynucleotidyltransferase, terminal, interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:16160
See related
Ensembl:ENSG00000101457 HPRD:16831; MIM:611388; Vega:OTTHUMG00000032610
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Tdif1; C20orf167; dJ447F3.4
Summary
DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM, Mar 2008]
Orthologs
Location:
20q13.12
Exon count:
13
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 20 NC_000020.11 (45791937..45811427)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (44420576..44440066)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene serine peptidase inhibitor, Kunitz type 5, pseudogene Neighboring gene WAP four-disulfide core domain 3 Neighboring gene ubiquitin conjugating enzyme E2 C Neighboring gene troponin C2, fast skeletal type

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
nucleosome binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
histone deacetylase complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
deoxynucleotidyltransferase terminal-interacting protein 1
Names
TdT binding protein
tdT-interacting factor 1
terminal deoxynucleotidyltransferase-interacting factor 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_052951.2NP_443183.1  deoxynucleotidyltransferase terminal-interacting protein 1

    See identical proteins and their annotated locations for NP_443183.1

    Status: VALIDATED

    Source sequence(s)
    AB035676, AI538721, BG720866, CD678110
    Consensus CDS
    CCDS13369.1
    UniProtKB/Swiss-Prot
    Q9H147
    Related
    ENSP00000361705, OTTHUMP00000031161, ENST00000372622, OTTHUMT00000079502

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p2 Primary Assembly

    Range
    45791937..45811427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018931.2 Alternate CHM1_1.1

    Range
    44323274..44343207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)