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Phb2 prohibitin 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 114766, updated on 26-May-2016
Official Symbol
Phb2provided by RGD
Official Full Name
prohibitin 2provided by RGD
Primary source
RGD:620203
See related
Ensembl:ENSRNOG00000012999
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Also known as
Bap; Bap37; Bap-37; Bcap27; Bcap37
Orthologs
Location:
4q42
Exon count:
10
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (157230769..157235375)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (224248365..224252971)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene complement component 1, s subcomponent Neighboring gene lysophosphatidylcholine acyltransferase 3 Neighboring gene EMG1 N1-specific pseudouridine methyltransferase Neighboring gene microRNA 3575 Neighboring gene microRNA 200c Neighboring gene microRNA 141

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
amide binding IEA
Inferred from Electronic Annotation
more info
 
amide binding ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
protein C-terminus binding IEA
Inferred from Electronic Annotation
more info
 
protein C-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein N-terminus binding IEA
Inferred from Electronic Annotation
more info
 
protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
mammary gland alveolus development IEA
Inferred from Electronic Annotation
more info
 
mammary gland alveolus development ISO
Inferred from Sequence Orthology
more info
 
mammary gland branching involved in thelarche IEA
Inferred from Electronic Annotation
more info
 
mammary gland branching involved in thelarche ISO
Inferred from Sequence Orthology
more info
 
mitochondrion organization IEA
Inferred from Electronic Annotation
more info
 
mitochondrion organization ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of intracellular estrogen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
negative regulation of intracellular estrogen receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
negative regulation of mammary gland epithelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 
negative regulation of mammary gland epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
 
negative regulation of sequence-specific DNA binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
negative regulation of sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell cycle G1/S phase transition IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cell cycle G1/S phase transition ISO
Inferred from Sequence Orthology
more info
 
positive regulation of exit from mitosis IEA
Inferred from Electronic Annotation
more info
 
positive regulation of exit from mitosis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of sequence-specific DNA binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
positive regulation of sequence-specific DNA binding transcription factor activity ISO
Inferred from Sequence Orthology
more info
 
protein import into nucleus, translocation IEA
Inferred from Electronic Annotation
more info
 
protein import into nucleus, translocation ISO
Inferred from Sequence Orthology
more info
 
protein stabilization IEA
Inferred from Electronic Annotation
more info
 
protein stabilization ISO
Inferred from Sequence Orthology
more info
 
regulation of branching involved in mammary gland duct morphogenesis IEA
Inferred from Electronic Annotation
more info
 
regulation of branching involved in mammary gland duct morphogenesis ISO
Inferred from Sequence Orthology
more info
 
NOT regulation of complement activation ISO
Inferred from Sequence Orthology
more info
 
sister chromatid cohesion IEA
Inferred from Electronic Annotation
more info
 
sister chromatid cohesion ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell periphery IEA
Inferred from Electronic Annotation
more info
 
cell periphery ISO
Inferred from Sequence Orthology
more info
 
cell surface IEA
Inferred from Electronic Annotation
more info
 
cell surface ISO
Inferred from Sequence Orthology
more info
 
cellular_component ND
No biological Data available
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
 
mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial outer membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nuclear matrix ISO
Inferred from Sequence Orthology
more info
 
nuclear matrix ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
 
protein complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
prohibitin-2
Names
B-cell receptor associated protein 37
B-cell receptor-associated protein 37
B-cell receptor-associated protein BAP37

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013035.1NP_001013053.1  prohibitin-2

    See identical proteins and their annotated locations for NP_001013053.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083705
    UniProtKB/Swiss-Prot
    Q5XIH7
    Related
    ENSRNOP00000017472, ENSRNOT00000017472
    Conserved Domains (2) summary
    cd03401
    Location:40235
    SPFH_prohibitin; Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily
    TIGR01932
    Location:39276
    hflC; HflC protein

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    157230769..157235375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    146256324..146260930
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)