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Actb actin, beta [ Mus musculus (house mouse) ]

Gene ID: 11461, updated on 18-Jan-2015
Official Symbol
Actbprovided by MGI
Official Full Name
actin, betaprovided by MGI
Primary source
MGI:MGI:87904
See related
Ensembl:ENSMUSG00000029580; Vega:OTTMUSG00000035960
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Actx; beta-actin; E430023M04Rik
Orthologs
See Actb in MapViewer
Location:
5 G2; 5 81.8 cM
Exon count:
6
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 5 NC_000071.6 (142903116..142906724, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31543 Neighboring gene F-box and leucine-rich repeat protein 18 Neighboring gene fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) Neighboring gene ring finger protein 216 Neighboring gene 60S ribosomal protein L9-like

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Tat protein binding ISO
Inferred from Sequence Orthology
more info
 
kinesin binding ISO
Inferred from Sequence Orthology
more info
 
nitric-oxide synthase binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to nucleosomal DNA binding ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
ATP-dependent chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
axonogenesis ISO
Inferred from Sequence Orthology
more info
 
cellular response to electrical stimulus ISO
Inferred from Sequence Orthology
more info
 
platelet aggregation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
MLL5-L complex ISO
Inferred from Sequence Orthology
more info
 
NuA4 histone acetyltransferase complex ISO
Inferred from Sequence Orthology
more info
 
axon ISO
Inferred from Sequence Orthology
more info
 
blood microparticle ISO
Inferred from Sequence Orthology
more info
 
cortical cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic ribonucleoprotein granule ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
focal adhesion ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
myelin sheath IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
 
ribonucleoprotein complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
actin, cytoplasmic 1
Names
actin, cytoplasmic 1
melanoma X-actin
A-X actin-like protein
actin, beta, cytoplasmic

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007393.3NP_031419.1  actin, cytoplasmic 1

    See proteins identical to NP_031419.1

    Status: PROVISIONAL

    Source sequence(s)
    AC144818
    Consensus CDS
    CCDS19833.1
    UniProtKB/TrEMBL
    B2RRX1
    UniProtKB/Swiss-Prot
    P60710
    Related
    ENSMUSP00000098066, OTTMUSP00000050934, ENSMUST00000100497, OTTMUST00000092248
    Conserved Domains (2) summary
    cd00012
    Location:8181
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    pfam00022
    Location:3375
    Actin; Actin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000071.6 

    Range
    142903116..142906724
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 

    Range
    139951533..139955141
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)