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Acta1 actin, alpha 1, skeletal muscle [ Mus musculus (house mouse) ]

Gene ID: 11459, updated on 11-Sep-2014
Official Symbol
Acta1provided by MGI
Official Full Name
actin, alpha 1, skeletal muscleprovided by MGI
Primary source
MGI:87902
See related
Ensembl:ENSMUSG00000031972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Acts; Acta-2; Actsk-1; AA959943
See Acta1 in Epigenomics, MapViewer
Location:
8 E2; 8 72.26 cM
Exon count:
8
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 8 NC_000074.6 (123891758..123894775, complement)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene centriole, cilia and spindle associated protein Neighboring gene uncharacterized LOC102640773 Neighboring gene uncharacterized LOC102640954 Neighboring gene uncharacterized LOC101056072 Neighboring gene nucleoporin 133 Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 10

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
skeletal muscle fiber development IDA
Inferred from Direct Assay
more info
PubMed 
skeletal muscle thin filament assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
actin filament ISO
Inferred from Sequence Orthology
more info
 
blood microparticle ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
extracellular vesicular exosome ISO
Inferred from Sequence Orthology
more info
 
protein complex ISO
Inferred from Sequence Orthology
more info
PubMed 
sarcomere ISO
Inferred from Sequence Orthology
more info
 
stress fiber ISO
Inferred from Sequence Orthology
more info
 
striated muscle thin filament ISO
Inferred from Sequence Orthology
more info
 
striated muscle thin filament TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
actin, alpha skeletal muscle
Names
actin, alpha skeletal muscle
alpha-actin-1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001272041.1NP_001258970.1  actin, alpha skeletal muscle

    See proteins identical to NP_001258970.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC147266, M12866
    Consensus CDS
    CCDS22764.1
    UniProtKB/Swiss-Prot
    P68134
    Conserved Domains (2) summary
    cd00012
    Location:10183
    Blast Score: 197
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    pfam00022
    Location:5377
    Blast Score: 1754
    Actin; Actin
  2. NM_009606.3NP_033736.1  actin, alpha skeletal muscle

    See proteins identical to NP_033736.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC147266, M12866
    Consensus CDS
    CCDS22764.1
    UniProtKB/Swiss-Prot
    P68134
    Related
    ENSMUSP00000034453, ENSMUST00000034453
    Conserved Domains (2) summary
    cd00012
    Location:10183
    Blast Score: 197
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
    pfam00022
    Location:5377
    Blast Score: 1754
    Actin; Actin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000074.6 

    Range
    123891758..123894775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000030.1 

    Range
    128158807..128161824
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)