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Dmrt1 doublesex and mab-3 related transcription factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 114498, updated on 26-May-2016
Official Symbol
Dmrt1provided by RGD
Official Full Name
doublesex and mab-3 related transcription factor 1provided by RGD
Primary source
RGD:621640
See related
Ensembl:ENSRNOG00000016075
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
Summary
transcription factor required for postnatal testis differentiation [RGD, Feb 2006]
Orthologs
Location:
1q51
Exon count:
5
Annotation release Status Assembly Chr Location
105 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (243477403..243582629)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (250737532..250841372)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene KN motif and ankyrin repeat domains 1 Neighboring gene uncharacterized LOC102554752 Neighboring gene RAN, member RAS oncogene family Neighboring gene doublesex and mab-3 related transcription factor 3 Neighboring gene doublesex and mab-3 related transcription factor 2

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
RNA polymerase II regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding ISO
Inferred from Sequence Orthology
more info
 
core promoter proximal region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
core promoter proximal region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity IBA
Inferred from Biological aspect of Ancestor
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding IEA
Inferred from Electronic Annotation
more info
 
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
Sertoli cell development IEA
Inferred from Electronic Annotation
more info
 
Sertoli cell development ISO
Inferred from Sequence Orthology
more info
 
Sertoli cell differentiation ISO
Inferred from Sequence Orthology
more info
 
cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 
cell morphogenesis ISO
Inferred from Sequence Orthology
more info
 
developmental process involved in reproduction ISO
Inferred from Sequence Orthology
more info
 
germ cell migration IEA
Inferred from Electronic Annotation
more info
 
germ cell migration ISO
Inferred from Sequence Orthology
more info
 
intracellular signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
male germ cell proliferation IEA
Inferred from Electronic Annotation
more info
 
male germ cell proliferation ISO
Inferred from Sequence Orthology
more info
 
male gonad development ISO
Inferred from Sequence Orthology
more info
 
male sex determination IEA
Inferred from Electronic Annotation
more info
 
male sex determination ISO
Inferred from Sequence Orthology
more info
 
male sex differentiation ISO
Inferred from Sequence Orthology
more info
 
male sex differentiation TAS
Traceable Author Statement
more info
PubMed 
negative regulation of meiotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
negative regulation of meiotic nuclear division ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
oocyte development IEA
Inferred from Electronic Annotation
more info
 
oocyte development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of male gonad development IEA
Inferred from Electronic Annotation
more info
 
positive regulation of male gonad development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of meiosis I IEA
Inferred from Electronic Annotation
more info
 
positive regulation of meiosis I ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitotic nuclear division IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitotic nuclear division ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
regulation of nodal signaling pathway IEA
Inferred from Electronic Annotation
more info
 
regulation of nodal signaling pathway ISO
Inferred from Sequence Orthology
more info
 
spermatogenesis IEA
Inferred from Electronic Annotation
more info
 
spermatogenesis ISO
Inferred from Sequence Orthology
more info
 
transcription from RNA polymerase II promoter IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
doublesex- and mab-3-related transcription factor 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_053706.1NP_446158.1  doublesex- and mab-3-related transcription factor 1

    See identical proteins and their annotated locations for NP_446158.1

    Status: PROVISIONAL

    Source sequence(s)
    AF379608
    UniProtKB/TrEMBL
    Q925A6
    Related
    ENSRNOP00000021779, ENSRNOT00000021779
    Conserved Domains (2) summary
    pfam00751
    Location:70116
    DM; DM DNA binding domain
    pfam12374
    Location:139194
    Dmrt1; Double-sex mab3 related transcription factor 1

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    243477403..243582629
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008760301.1XP_008758523.1  

    Conserved Domains (2) summary
    pfam00751
    Location:70116
    DM; DM DNA binding domain
    pfam12374
    Location:139194
    Dmrt1; Double-sex mab3 related transcription factor 1

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    220344915..220443789
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)