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Prss1 protease, serine 1 (trypsin 1) [ Mus musculus (house mouse) ]

Gene ID: 114228, updated on 8-May-2016
Official Symbol
Prss1provided by MGI
Official Full Name
protease, serine 1 (trypsin 1)provided by MGI
Primary source
MGI:MGI:98839
See related
Ensembl:ENSMUSG00000062751 Vega:OTTMUSG00000026897
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Try1; Try-1; Trygn16
Location:
6 B1; 6 19.6 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 6 NC_000072.6 (41458930..41463786)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (41408929..41413785)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene T cell receptor beta chain Neighboring gene predicted pseudogene 5409 Neighboring gene predicted gene 10334 Neighboring gene proline-rich polypeptide 3 pseudogene Neighboring gene protease, serine 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
Products Interactant Other Gene Complex Source Pubs Description

Gene Ontology Provided by MGI

Function Evidence Code Pubs
serine-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
digestion IBA
Inferred from Biological aspect of Ancestor
more info
 
proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
protease, serine, 1
Names
protease, serine, 1 (trypsin 1)
trypsin 1
trypsinogen 16
NP_444473.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_006980.1 

    Range
    568136..572992
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_053243.2NP_444473.1  protease, serine, 1 precursor

    See identical proteins and their annotated locations for NP_444473.1

    Status: VALIDATED

    Source sequence(s)
    AC153854
    Consensus CDS
    CCDS20049.1
    UniProtKB/TrEMBL
    Q9Z1R9
    Related
    ENSMUSP00000031910, OTTMUSP00000033342, ENSMUST00000031910, OTTMUST00000066517
    Conserved Domains (2) summary
    smart00020
    Location:23239
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:24242
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p3 C57BL/6J

    Range
    41458930..41463786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000028.1 Alternate Mm_Celera

    Range
    41412491..41417345
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)