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ITPR2 inositol 1,4,5-trisphosphate receptor type 2 [ Zalophus californianus (California sea lion) ]

Gene ID: 113921922, updated on 11-Apr-2024

Summary

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Gene symbol
ITPR2
Gene description
inositol 1,4,5-trisphosphate receptor type 2
See related
EnsemblRapid:ENSZCAG00025015912
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
58
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 9 NC_045603.1 (79897021..80397001)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020884870.1 (57773389..58274223, complement)

Chromosome 9 - NC_045603.1Genomic Context describing neighboring genes Neighboring gene integrator complex subunit 13 Neighboring gene 60S ribosomal protein L26-like Neighboring gene uncharacterized LOC113921925 Neighboring gene sarcospan Neighboring gene prostaglandin reductase 1-like Neighboring gene basic helix-loop-helix family member e41

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables inositol 1,4,5 trisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inositol 1,4,5-trisphosphate-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inositol 1,4,5-trisphosphate receptor type 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045603.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    79897021..80397001
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027593395.2 → XP_027449196.2  inositol 1,4,5-trisphosphate receptor type 2 isoform X1

    UniProtKB/TrEMBL
    A0A6J2D0I0
    Related
    ENSZCAP00025025052.1, ENSZCAT00025028436.1
    Conserved Domains (5) summary
    pfam00520
    Location:2290 → 2552
    Ion_trans; Ion transport protein
    pfam01365
    Location:473 → 670
    RYDR_ITPR; RIH domain
    pfam02815
    Location:232 → 432
    MIR; MIR domain
    pfam08454
    Location:1915 → 2022
    RIH_assoc; RyR and IP3R Homology associated
    pfam08709
    Location:4 → 228
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

  2. XM_027593396.2 → XP_027449197.2  inositol 1,4,5-trisphosphate receptor type 2 isoform X2

    UniProtKB/TrEMBL
    A0A6J2D2U6
    Conserved Domains (5) summary
    pfam00520
    Location:2106 → 2368
    Ion_trans; Ion transport protein
    pfam01365
    Location:289 → 486
    RYDR_ITPR; RIH domain
    pfam02815
    Location:48 → 248
    MIR; MIR domain
    pfam08454
    Location:1731 → 1838
    RIH_assoc; RyR and IP3R Homology associated
    cl19745
    Location:2 → 44
    Ins145_P3_rec; Inositol 1,4,5-trisphosphate/ryanodine receptor

RNA

  1. XR_003519864.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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