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PIK3IP1 phosphoinositide-3-kinase interacting protein 1 [ Homo sapiens (human) ]

Gene ID: 113791, updated on 26-May-2016
Official Symbol
PIK3IP1provided by HGNC
Official Full Name
phosphoinositide-3-kinase interacting protein 1provided by HGNC
Primary source
HGNC:HGNC:24942
See related
Ensembl:ENSG00000100100 HPRD:17518; Vega:OTTHUMG00000151256
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HGFL; hHGFL(S)
Orthologs
Location:
22q12.2
Exon count:
6
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 22 NC_000022.11 (31281593..31292534, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (31677579..31688833, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene ring finger protein 185 Neighboring gene LIM domain kinase 2 Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14B pseudogene 1 Neighboring gene uncharacterized LOC105372997 Neighboring gene RNA, 5S ribosomal pseudogene 496

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC17330

Gene Ontology Provided by GOA

Function Evidence Code Pubs
phosphatidylinositol 3-kinase catalytic subunit binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
phosphoinositide-3-kinase-interacting protein 1
Names
kringle domain-containing protein HGFL

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135911.1NP_001129383.1  phosphoinositide-3-kinase-interacting protein 1 isoform 2 precursor

    See identical proteins and their annotated locations for NP_001129383.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) is missing the penultimate coding exon compared to transcript variant 1. This results in a frame-shift, early translation termination and a shorter isoform (2) with a distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AC002073, AK299397, AW005175, DC412134
    Consensus CDS
    CCDS46690.1
    UniProtKB/Swiss-Prot
    Q96FE7
    Related
    ENSP00000415608, ENST00000441972
    Conserved Domains (1) summary
    cd00108
    Location:22102
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
  2. NM_052880.4NP_443112.2  phosphoinositide-3-kinase-interacting protein 1 isoform 1 precursor

    See identical proteins and their annotated locations for NP_443112.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC002073, AW005175, DC412134
    Consensus CDS
    CCDS13893.1
    UniProtKB/Swiss-Prot
    Q96FE7
    UniProtKB/TrEMBL
    A0A024R1M3
    Related
    ENSP00000215912, OTTHUMP00000199499, ENST00000215912, OTTHUMT00000321939
    Conserved Domains (1) summary
    cd00108
    Location:22102
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p2 Primary Assembly

    Range
    31281593..31292534 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018933.2 Alternate CHM1_1.1

    Range
    31637394..31648335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)