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Npr2 natriuretic peptide receptor 2 [ Urocitellus parryii (Arctic ground squirrel) ]

Gene ID: 113201201, updated on 15-Mar-2024

Summary

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Gene symbol
Npr2
Gene description
natriuretic peptide receptor 2
See related
Ensembl:ENSUPAG00010017675
Gene type
protein coding
RefSeq status
MODEL
Organism
Urocitellus parryii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Urocitellus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current ASM342692v1 (GCF_003426925.1) Unplaced Scaffold NW_020539907.1 (9801386..9819910, complement)

NW_020539907.1Genomic Context describing neighboring genes Neighboring gene histidine triad nucleotide binding protein 2 Neighboring gene sperm associated antigen 8 Neighboring gene microseminoprotein, prostate associated Neighboring gene RGP1 homolog, RAB6A GEF complex partner 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020539907 Unplaced Scaffold Reference ASM342692v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanylate cyclase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables natriuretic peptide receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cGMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in receptor guanylyl cyclase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
atrial natriuretic peptide receptor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Urocitellus parryii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM342692v1

Genomic

  1. NW_020539907.1 Reference ASM342692v1

    Range
    9801386..9819910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026414812.1 → XP_026270597.1  atrial natriuretic peptide receptor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8D2I330
    Related
    ENSUPAP00010022236.1, ENSUPAT00010025316.1
    Conserved Domains (4) summary
    smart00044
    Location:825 → 1009
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:518 → 792
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    cd06384
    Location:26 → 421
    PBP1_NPR_B; ligand-binding domain of type B natriuretic peptide receptor
    pfam07701
    Location:798 → 846
    HNOBA; Heme NO binding associated

  2. XM_026414821.1 → XP_026270606.1  atrial natriuretic peptide receptor 2 isoform X2

    UniProtKB/TrEMBL
    A0A8D2I8Y5
    Related
    ENSUPAP00010022249.1, ENSUPAT00010025331.1
    Conserved Domains (4) summary
    smart00044
    Location:800 → 984
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
    cd14042
    Location:486 → 767
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    cd06384
    Location:26 → 421
    PBP1_NPR_B; ligand-binding domain of type B natriuretic peptide receptor
    pfam07701
    Location:773 → 821
    HNOBA; Heme NO binding associated

  3. XM_026414829.1 → XP_026270614.1  atrial natriuretic peptide receptor 2 isoform X3

    Conserved Domains (4) summary
    cd14042
    Location:518 → 792
    PK_GC-A_B; Pseudokinase domain of the membrane Guanylate Cyclase receptors, GC-A and GC-B
    pfam07701
    Location:801 → 846
    HNOBA; Heme NO binding associated
    cl10011
    Location:26 → 421
    Periplasmic_Binding_Protein_Type_1; Type 1 periplasmic binding fold superfamily
    cl27308
    Location:825 → 908
    CYCc; Adenylyl- / guanylyl cyclase, catalytic domain
Nucleotide Protein
Heading Accession and Version

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