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Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 [ Mus musculus (house mouse) ]

Gene ID: 11305, updated on 28-May-2016
Official Symbol
Abca2provided by MGI
Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 2provided by MGI
Primary source
MGI:MGI:99606
See related
Ensembl:ENSMUSG00000026944 Vega:OTTMUSG00000012108
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Abc2; AI413825; mKIAA1062; D2H0S1474E
Orthologs
Location:
2 17.25 cM; 2 A2-B
Exon count:
50
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (25428604..25448544)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (25284194..25304059)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene neural proliferation, differentiation and control 1 Neighboring gene fucosyltransferase 7 Neighboring gene microRNA 3087 Neighboring gene cDNA sequence BC029214 Neighboring gene chloride intracellular channel 3 Neighboring gene prostaglandin D2 synthase (brain)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • ABC transporters, organism-specific biosystem (from KEGG)
    ABC transporters, organism-specific biosystemThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of ...
  • ABC transporters, conserved biosystem (from KEGG)
    ABC transporters, conserved biosystemThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of ...
  • Lysosome, organism-specific biosystem (from KEGG)
    Lysosome, organism-specific biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...
  • Lysosome, conserved biosystem (from KEGG)
    Lysosome, conserved biosystemLysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding ISO
Inferred from Sequence Orthology
more info
 
ATPase activity ISO
Inferred from Sequence Orthology
more info
 
ATPase activity, coupled to transmembrane movement of substances IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cholesterol efflux IBA
Inferred from Biological aspect of Ancestor
more info
 
cholesterol metabolic process ISO
Inferred from Sequence Orthology
more info
 
phospholipid efflux IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of intracellular cholesterol transport ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasmic, membrane-bounded vesicle ISO
Inferred from Sequence Orthology
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
 
lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
lysosome ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
ATP-binding cassette sub-family A member 2
Names
ATP-binding cassette 2
ATP-binding cassette transporter 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_007379.2NP_031405.2  ATP-binding cassette sub-family A member 2

    See identical proteins and their annotated locations for NP_031405.2

    Status: VALIDATED

    Source sequence(s)
    AK169438, AL732557
    Consensus CDS
    CCDS15773.1
    UniProtKB/TrEMBL
    A2AJ26
    Related
    ENSMUSP00000099983, OTTMUSP00000013051, ENSMUST00000102919, OTTMUST00000028850
    Conserved Domains (2) summary
    TIGR01257
    Location:12367
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20502273
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    25428604..25448544
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006497612.1XP_006497675.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:12368
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20512274
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  2. XM_006497614.2XP_006497677.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:162356
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20392262
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  3. XM_006497613.2XP_006497676.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:272367
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20502273
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  4. XM_006497615.2XP_006497678.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:102350
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20332256
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  5. XM_006497616.2XP_006497679.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:102349
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20322255
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  6. XM_006497609.1XP_006497672.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:582398
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20812304
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  7. XM_006497611.1XP_006497674.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:582379
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20622285
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
  8. XM_006497610.1XP_006497673.1  

    Conserved Domains (2) summary
    TIGR01257
    Location:582397
    rim_protein; retinal-specific rim ABC transporter
    cd03263
    Location:20802303
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    25156185..25176102
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)