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bace1 beta-secretase 1 [ Astatotilapia calliptera (eastern happy) ]

Gene ID: 113036060, updated on 15-Mar-2024

Summary

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Gene symbol
bace1
Gene description
beta-secretase 1
See related
Ensembl:ENSACLG00000011176
Gene type
protein coding
RefSeq status
MODEL
Organism
Astatotilapia calliptera
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Haplochromini; Astatotilapia
Orthologs
human zebrafish all
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Genomic context

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See bace1 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
9
Annotation release Status Assembly Chr Location
100 current fAstCal1.2 (GCF_900246225.1) 14 NC_039315.1 (29927189..29942804)

Chromosome 14 - NC_039315.1Genomic Context describing neighboring genes Neighboring gene T-box transcription factor TBX1-A-like Neighboring gene uncharacterized LOC113036064 Neighboring gene apolipoprotein A-Ib Neighboring gene proprotein convertase subtilisin/kexin type 7 Neighboring gene transgelin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_039315.1 Chromosome 14 Reference fAstCal1.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-secretase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Astatotilapia calliptera Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fAstCal1.2 Primary Assembly

Genomic

  1. NC_039315.1 Reference fAstCal1.2 Primary Assembly

    Range
    29927189..29942804
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026192099.1 → XP_026047884.1  beta-secretase 1

    UniProtKB/TrEMBL
    A0A3P8PH74
    Related
    ENSACLP00000016400.1, ENSACLT00000016786.1
    Conserved Domains (1) summary
    cd05473
    Location:89 → 454
    beta_secretase_like; Beta-secretase, aspartic-acid protease important in the pathogenesis of Alzheimer's disease
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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