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CIT citron rho-interacting serine/threonine kinase [ Vulpes vulpes (red fox) ]

Gene ID: 112932903, updated on 15-Mar-2024

Summary

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Gene symbol
CIT
Gene description
citron rho-interacting serine/threonine kinase
See related
Ensembl:ENSVVUG00000013447
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See CIT in Genome Data Viewer
Location:
chromosome: Un
Exon count:
47
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356553.1 (4596462..4748216, complement)

NW_020356553.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 233 Neighboring gene protein kinase AMP-activated non-catalytic subunit beta 1 Neighboring gene BICD family-like cargo adapter 1 Neighboring gene BICD family like cargo adaptor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356553 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actomyosin structure organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-threonine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
citron Rho-interacting kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356553.1 Reference VulVul2.2 Primary Assembly

    Range
    4596462..4748216 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026015882.1 → XP_025871667.1  citron Rho-interacting kinase isoform X1

    UniProtKB/TrEMBL
    A0A3Q7UEP5
    Related
    ENSVVUP00000020434.1, ENSVVUT00000027102.1
    Conserved Domains (5) summary
    smart00036
    Location:1511 → 1807
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd00029
    Location:1281 → 1329
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd05601
    Location:1 → 298
    STKc_CRIK; Catalytic domain of the Serine/Threonine Kinase, Citron Rho-interacting kinase
    pfam00169
    Location:1362 → 1481
    PH; PH domain
    cl25732
    Location:350 → 1164
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_026015883.1 → XP_025871668.1  citron Rho-interacting kinase isoform X2

    UniProtKB/TrEMBL
    A0A3Q7TPK4
    Conserved Domains (5) summary
    smart00036
    Location:1198 → 1494
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd00029
    Location:968 → 1016
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam00169
    Location:1049 → 1168
    PH; PH domain
    cl25732
    Location:28 → 898
    SMC_N; RecF/RecN/SMC N terminal domain
    cl25751
    Location:1510 → 1598
    DUF4045; Domain of unknown function (DUF4045)

  3. XM_026015885.1 → XP_025871670.1  citron Rho-interacting kinase isoform X2

    UniProtKB/TrEMBL
    A0A3Q7TPK4
    Conserved Domains (5) summary
    smart00036
    Location:1198 → 1494
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd00029
    Location:968 → 1016
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam00169
    Location:1049 → 1168
    PH; PH domain
    cl25732
    Location:28 → 898
    SMC_N; RecF/RecN/SMC N terminal domain
    cl25751
    Location:1510 → 1598
    DUF4045; Domain of unknown function (DUF4045)

  4. XM_026015886.1 → XP_025871671.1  citron Rho-interacting kinase isoform X3

    UniProtKB/TrEMBL
    A0A3Q7U1U1
    Conserved Domains (5) summary
    smart00036
    Location:1178 → 1474
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd00029
    Location:948 → 996
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam00169
    Location:1029 → 1148
    PH; PH domain
    cl25732
    Location:8 → 878
    SMC_N; RecF/RecN/SMC N terminal domain
    cl25751
    Location:1490 → 1578
    DUF4045; Domain of unknown function (DUF4045)
Nucleotide Protein Strain
Heading Accession and Version

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