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CD44 CD44 molecule (IN blood group) [ Vulpes vulpes (red fox) ]

Gene ID: 112930492, updated on 15-Mar-2024

Summary

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Gene symbol
CD44
Gene description
CD44 molecule (IN blood group)
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356529.1 (1225246..1315144, complement)

NW_020356529.1Genomic Context describing neighboring genes Neighboring gene peptidase domain containing associated with muscle regeneration 1 Neighboring gene actin-related protein 2/3 complex subunit 3 pseudogene Neighboring gene solute carrier family 1 member 2 Neighboring gene pyruvate dehydrogenase complex component X Neighboring gene APAF1 interacting protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356529 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basolateral plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of macrophage migration inhibitory factor receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CD44 antigen
Names
CD44 molecule (Indian blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356529.1 Reference VulVul2.2 Primary Assembly

    Range
    1225246..1315144 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026012849.1 → XP_025868634.1  CD44 antigen

    UniProtKB/TrEMBL
    A0A3Q7SX96
    Conserved Domains (2) summary
    cd03516
    Location:26 → 170
    Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...
    cl02571
    Location:122 → 243
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
Nucleotide Protein Strain
Heading Accession and Version

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