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FGFR4 fibroblast growth factor receptor 4 [ Vulpes vulpes (red fox) ]

Gene ID: 112925658, updated on 15-Mar-2024

Summary

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Gene symbol
FGFR4
Gene description
fibroblast growth factor receptor 4
See related
Ensembl:ENSVVUG00000001227
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See FGFR4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356437.1 (17384302..17395210, complement)

NW_020356437.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112925651 Neighboring gene nuclear receptor binding SET domain protein 1 Neighboring gene coiled-coil-helix-coiled-coil-helix domain-containing protein 2 pseudogene Neighboring gene normal mucosa of esophagus-specific gene 1 protein pseudogene Neighboring gene zinc finger protein 346 Neighboring gene ubiquitin interaction motif containing 1 Neighboring gene U4 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356437 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fibroblast growth factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fibroblast growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of bile acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibroblast growth factor receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356437.1 Reference VulVul2.2 Primary Assembly

    Range
    17384302..17395210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026006484.1 → XP_025862269.1  fibroblast growth factor receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A3Q7TLV7
    Related
    ENSVVUP00000001504.1, ENSVVUT00000002185.1
    Conserved Domains (5) summary
    smart00408
    Location:50 → 107
    IGc2; Immunoglobulin C-2 Type
    cd00096
    Location:249 → 252
    Ig; Ig strand A [structural motif]
    cd05857
    Location:147 → 241
    IgI_2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; member of the I-set of IgSF domains
    cl11960
    Location:249 → 351
    Ig; Immunoglobulin domain
    cl21453
    Location:454 → 767
    PKc_like; Protein Kinases, catalytic domain

  2. XM_026006492.1 → XP_025862277.1  fibroblast growth factor receptor 4 isoform X4

    UniProtKB/TrEMBL
    A0A3Q7TLW3
    Conserved Domains (4) summary
    cd05858
    Location:324 → 411
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    smart00408
    Location:110 → 167
    IGc2; Immunoglobulin C-2 Type
    cl11960
    Location:217 → 301
    Ig; Immunoglobulin domain
    cl21453
    Location:459 → 759
    PKc_like; Protein Kinases, catalytic domain

  3. XM_026006478.1 → XP_025862263.1  fibroblast growth factor receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A3Q7SYU4
    Conserved Domains (4) summary
    cd05858
    Location:324 → 411
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    smart00408
    Location:110 → 167
    IGc2; Immunoglobulin C-2 Type
    cl11960
    Location:217 → 301
    Ig; Immunoglobulin domain
    cl21453
    Location:514 → 781
    PKc_like; Protein Kinases, catalytic domain

  4. XM_026006487.1 → XP_025862272.1  fibroblast growth factor receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A3Q7TLV7
    Conserved Domains (5) summary
    smart00408
    Location:50 → 107
    IGc2; Immunoglobulin C-2 Type
    cd00096
    Location:249 → 252
    Ig; Ig strand A [structural motif]
    cd05857
    Location:147 → 241
    IgI_2_FGFR; Second immunoglobulin (Ig)-like domain of fibroblast growth factor (FGF) receptor; member of the I-set of IgSF domains
    cl11960
    Location:249 → 351
    Ig; Immunoglobulin domain
    cl21453
    Location:454 → 767
    PKc_like; Protein Kinases, catalytic domain

  5. XM_026006472.1 → XP_025862257.1  fibroblast growth factor receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A3Q7TLU3
    Conserved Domains (4) summary
    cd05858
    Location:324 → 411
    Ig3_FGFR-2; Third immunoglobulin (Ig)-like domain of fibroblast growth factor receptor 2 (FGFR2)
    smart00408
    Location:110 → 167
    IGc2; Immunoglobulin C-2 Type
    cl11960
    Location:217 → 301
    Ig; Immunoglobulin domain
    cl21453
    Location:514 → 827
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein Strain
Heading Accession and Version

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