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NGEF neuronal guanine nucleotide exchange factor [ Vulpes vulpes (red fox) ]

Gene ID: 112925453, updated on 15-Mar-2024

Summary

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Gene symbol
NGEF
Gene description
neuronal guanine nucleotide exchange factor
See related
Ensembl:ENSVVUG00000025486
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes vulpes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
100 current VulVul2.2 (GCF_003160815.1) Unplaced Scaffold NW_020356492.1 (2760249..2801982)

NW_020356492.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112925491 Neighboring gene neuraminidase 2 Neighboring gene secondary ossification center associated regulator of chondrocyte maturation Neighboring gene probable ribosome biogenesis protein RLP24 pseudogene Neighboring gene GRB10 interacting GYF protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020356492 Unplaced Scaffold Reference VulVul2.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephexin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes vulpes Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VulVul2.2 Primary Assembly

Genomic

  1. NW_020356492.1 Reference VulVul2.2 Primary Assembly

    Range
    2760249..2801982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026006181.1 → XP_025861966.1  ephexin-1

    UniProtKB/TrEMBL
    A0A3Q7T0W7
    Related
    ENSVVUP00000035426.1, ENSVVUT00000046668.1
    Conserved Domains (3) summary
    cd11939
    Location:531 → 585
    SH3_ephexin1; Src homology 3 domain of the Rho guanine nucleotide exchange factor, ephexin-1 (also called NGEF or ARHGEF27)
    cd01221
    Location:392 → 518
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain
    pfam00621
    Location:192 → 370
    RhoGEF; RhoGEF domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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