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USP45 ubiquitin specific peptidase 45 [ Puma concolor (puma) ]

Gene ID: 112862108, updated on 15-Mar-2024

Summary

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Gene symbol
USP45
Gene description
ubiquitin specific peptidase 45
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020339445.1 (60887303..60956194)

NW_020339445.1Genomic Context describing neighboring genes Neighboring gene cyclin C Neighboring gene thiosulfate sulfurtransferase like domain containing 3 Neighboring gene PNN interacting serine and arginine rich protein Neighboring gene coenzyme Q3, methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020339445 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 45

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020339445.1 Reference PumCon1.0 Primary Assembly

    Range
    60887303..60956194
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025925347.1 → XP_025781132.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X1

    UniProtKB/TrEMBL
    A0A6P6HZC2
    Conserved Domains (3) summary
    cd02667
    Location:602 → 810
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:62 → 132
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:192 → 388
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  2. XM_025925349.1 → XP_025781134.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X3

    UniProtKB/TrEMBL
    A0A6P6HZU5
    Conserved Domains (3) summary
    cd02667
    Location:544 → 752
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:62 → 132
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:192 → 330
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  3. XM_025925348.1 → XP_025781133.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X2

    UniProtKB/TrEMBL
    A0A6P6I1B6
    Conserved Domains (3) summary
    cd02667
    Location:601 → 809
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:61 → 131
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:191 → 387
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  4. XM_025925350.1 → XP_025781135.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X4

    UniProtKB/TrEMBL
    A0A6P6HZ82
    Conserved Domains (3) summary
    cd02667
    Location:543 → 751
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam02148
    Location:61 → 131
    zf-UBP; Zn-finger in ubiquitin-hydrolases and other protein
    cl02553
    Location:191 → 329
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...

  5. XM_025925351.1 → XP_025781136.1  ubiquitin carboxyl-terminal hydrolase 45 isoform X5

    UniProtKB/TrEMBL
    A0A6P6HZN7
    Conserved Domains (1) summary
    cd02667
    Location:241 → 449
    Peptidase_C19K; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
Nucleotide Protein
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