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TP53RK TP53 regulating kinase [ Homo sapiens (human) ]

Gene ID: 112858, updated on 11-Sep-2014
Official Symbol
TP53RKprovided by HGNC
Official Full Name
TP53 regulating kinaseprovided by HGNC
Primary source
HGNC:HGNC:16197
Locus tag
RP1-28H20.1
See related
Ensembl:ENSG00000172315; HPRD:12276; MIM:608679; Vega:OTTHUMG00000085887
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRPK; BUD32; Nori-2; Nori-2p; dJ101A2; C20orf64
See TP53RK in Epigenomics, MapViewer
Location:
20q13.2
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 20 NC_000020.11 (46684365..46689637, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (45313004..45318301, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene zinc finger protein 334 Neighboring gene osteoclast stimulatory transmembrane protein Neighboring gene solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 Neighboring gene solute carrier family 2 (facilitated glucose transporter), member 10 Neighboring gene ribosomal protein L13 pseudogene 14

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
p53 binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
lipopolysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
protein phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
tRNA processing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
TP53-regulating kinase
Names
TP53-regulating kinase
p53-related protein kinase
EKC/KEOPS complex subunit TP53RK
atypical serine/threonine protein kinase TP53RK
NP_291028.3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_033550.3NP_291028.3  TP53-regulating kinase

    See proteins identical to NP_291028.3

    Status: VALIDATED

    Source sequence(s)
    AB017505, BC035461, BM702732
    Consensus CDS
    CCDS13401.1
    UniProtKB/Swiss-Prot
    Q96S44
    Related
    ENSP00000361186, OTTHUMP00000108264, ENST00000372114, OTTHUMT00000193687
    Conserved Domains (1) summary
    COG3642
    Location:36253
    Blast Score: 593
    COG3642; Mn2+-dependent serine/threonine protein kinase [Signal transduction mechanisms]

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000020.11 

    Range
    46684365..46689637
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

  1. AC_000152.1 

    Range
    42054239..42059511
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018931.2 

    Range
    45215992..45221264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)