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SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 [ Puma concolor (puma) ]

Gene ID: 112857541, updated on 15-Mar-2024

Summary

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Gene symbol
SRGAP3
Gene description
SLIT-ROBO Rho GTPase activating protein 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020338156.1 (13704364..13975839, complement)

NW_020338156.1Genomic Context describing neighboring genes Neighboring gene oxytocin receptor Neighboring gene RAD18 E3 ubiquitin protein ligase Neighboring gene THUMP domain containing 3 Neighboring gene SET domain containing 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020338156 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SLIT-ROBO Rho GTPase-activating protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020338156.1 Reference PumCon1.0 Primary Assembly

    Range
    13704364..13975839 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025920900.1 → XP_025776685.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A6P6HLJ1
    Conserved Domains (3) summary
    cd07684
    Location:26 → 278
    F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
    cd11955
    Location:724 → 776
    SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
    cd04383
    Location:481 → 665
    RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...

  2. XM_025920893.1 → XP_025776678.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A6P6HN20
    Conserved Domains (3) summary
    cd07684
    Location:26 → 278
    F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
    cd11955
    Location:748 → 800
    SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
    cd04383
    Location:502 → 689
    RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...

  3. XM_025920885.1 → XP_025776670.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A6P6HLH6
    Conserved Domains (3) summary
    cd07684
    Location:26 → 278
    F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
    cd11955
    Location:758 → 810
    SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
    cd04383
    Location:510 → 699
    RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...
Nucleotide Protein
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