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ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 [ Callorhinus ursinus (northern fur seal) ]

Gene ID: 112827688, updated on 15-Mar-2024

Summary

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Gene symbol
ACAP2
Gene description
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
See related
EnsemblRapid:ENSCURG00000003630
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinus ursinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Callorhinus
Orthologs
human mouse all
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Genomic context

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See ACAP2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
100 current ASM326570v1 (GCF_003265705.1) Unplaced Scaffold NW_020312785.1 (63272001..63416559)

NW_020312785.1Genomic Context describing neighboring genes Neighboring gene POU domain, class 5, transcription factor 1 pseudogene Neighboring gene apolipoprotein D Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 2 Neighboring gene U4 spliceosomal RNA Neighboring gene U1 spliceosomal RNA Neighboring gene xyloside xylosyltransferase 1 Neighboring gene cytochrome b-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020312785 Unplaced Scaffold Reference ASM326570v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinus ursinus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM326570v1 Primary Assembly

Genomic

  1. NW_020312785.1 Reference ASM326570v1 Primary Assembly

    Range
    63272001..63416559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025876382.1 → XP_025732167.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A3Q7PQ82
    Related
    ENSCURP00000005848.1, ENSCURT00000006981.1
    Conserved Domains (5) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    cd13250
    Location:269 → 365
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:638 → 671
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:645 → 726
    Ank_2; Ankyrin repeats (3 copies)
    cd08851
    Location:399 → 513
    ArfGap_ACAP2; ArfGAP domain of ACAP2 (ArfGAP with Coiled-coil, ANK repeat and PH domains 2)

  2. XM_025876391.1 → XP_025732176.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A3Q7QW63
    Related
    ENSCURP00000005951.1, ENSCURT00000007102.1
    Conserved Domains (5) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    smart00105
    Location:402 → 517
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:610 → 726
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:269 → 365
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:638 → 671
    ANK; ANK repeat [structural motif]

  3. XM_025876399.1 → XP_025732184.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A3Q7PEC6
    Related
    ENSCURP00000005938.1, ENSCURT00000007085.1
    Conserved Domains (5) summary
    smart00105
    Location:344 → 459
    ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
    cd00204
    Location:552 → 668
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    cd13250
    Location:211 → 307
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    sd00045
    Location:580 → 613
    ANK; ANK repeat [structural motif]
    cl12013
    Location:18 → 159
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein
Heading Accession and Version

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