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KRT71 keratin 71 [ Homo sapiens (human) ]

Gene ID: 112802, updated on 8-May-2016
Official Symbol
KRT71provided by HGNC
Official Full Name
keratin 71provided by HGNC
Primary source
HGNC:HGNC:28927
See related
Ensembl:ENSG00000139648 HPRD:09745; MIM:608245; Vega:OTTHUMG00000167831
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HYPT13; K6IRS1; KRT6IRS; KRT6IRS1
Summary
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene encodes a protein that is expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q13.[provided by RefSeq, Jun 2009]
Orthologs
Location:
12q13.13
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 12 NC_000012.12 (52543909..52553147, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (52937693..52946931, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene keratin 6A Neighboring gene keratin 5 Neighboring gene keratin 74 Neighboring gene keratin 72 Neighboring gene keratin 73

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC119390, MGC119391

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
structural molecule activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
hair follicle morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
intermediate filament organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome IDA
Inferred from Direct Assay
more info
PubMed 
keratin filament IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
keratin, type II cytoskeletal 71
Names
CK-71
K71
cytokeratin-71
hK6irs
hK6irs1
keratin 6 irs
keratin 71, type II
keratin-71
type II inner root sheath-specific keratin-K6irs1
type-II keratin Kb34

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_012426.1 RefSeqGene

    Range
    5001..14239
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_033448.2NP_258259.1  keratin, type II cytoskeletal 71

    See identical proteins and their annotated locations for NP_258259.1

    Status: REVIEWED

    Source sequence(s)
    AJ308599, AK122795
    Consensus CDS
    CCDS8831.1
    UniProtKB/Swiss-Prot
    Q3SY84
    Related
    ENSP00000267119, OTTHUMP00000236990, ENST00000267119, OTTHUMT00000396487
    Conserved Domains (2) summary
    pfam00038
    Location:129442
    Filament; Intermediate filament protein
    cl19885
    Location:198423
    Sec6; Exocyst complex component Sec6

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p2 Primary Assembly

    Range
    52543909..52553147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018923.2 Alternate CHM1_1.1

    Range
    52904547..52913785 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)