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GSDMD gasdermin D [ Canis lupus dingo (dingo) ]

Gene ID: 112662264, updated on 3-Apr-2024

Summary

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Gene symbol
GSDMD
Gene description
gasdermin D
See related
Ensembl:ENSCAFG00020018657
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 13 NC_064255.1 (37581460..37587147)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 13 NC_049956.1 (38983764..38989482)

Chromosome 13 - NC_064255.1Genomic Context describing neighboring genes Neighboring gene MAF bZIP transcription factor A Neighboring gene zinc finger CCCH-type containing 3 Neighboring gene maestro heat like repeat family member 6 Neighboring gene nicotinate phosphoribosyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-4,5-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylserine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyroptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NLRP3 inflammasome complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gasdermin-D

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064255.1 Reference ASM325472v2

    Range
    37581460..37587147
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035713165.2 → XP_035569058.1  gasdermin-D isoform X3

    UniProtKB/TrEMBL
    A0A8C0L4Q4, A0A8C0SB41, A0A8I3NWY6, A0A8P0PNE4
    Conserved Domains (2) summary
    pfam04598
    Location:4 → 238
    Gasdermin; Gasdermin family
    pfam17708
    Location:268 → 440
    Gasdermin_C; Gasdermin PUB domain

  2. XM_049092843.1 → XP_048948800.1  gasdermin-D isoform X2

  3. XM_035713169.2 → XP_035569062.1  gasdermin-D isoform X3

    UniProtKB/TrEMBL
    A0A8C0L4Q4, A0A8C0SB41, A0A8I3NWY6, A0A8P0PNE4
    Conserved Domains (2) summary
    pfam04598
    Location:4 → 238
    Gasdermin; Gasdermin family
    pfam17708
    Location:268 → 440
    Gasdermin_C; Gasdermin PUB domain

  4. XM_025450854.3 → XP_025306639.1  gasdermin-D isoform X1

    UniProtKB/TrEMBL
    A0A8C0PQH0, A0A8I3NWY6, A0A8P0NMS2, A0A8P0PNE4
    Conserved Domains (2) summary
    pfam04598
    Location:4 → 238
    Gasdermin; Gasdermin family
    pfam17708
    Location:307 → 479
    Gasdermin_C; Gasdermin PUB domain

  5. XM_035713144.2 → XP_035569037.1  gasdermin-D isoform X1

    UniProtKB/TrEMBL
    A0A8C0PQH0, A0A8I3NWY6, A0A8P0NMS2, A0A8P0PNE4
    Conserved Domains (2) summary
    pfam04598
    Location:4 → 238
    Gasdermin; Gasdermin family
    pfam17708
    Location:307 → 479
    Gasdermin_C; Gasdermin PUB domain

  6. XM_025450853.3 → XP_025306638.1  gasdermin-D isoform X1

    UniProtKB/TrEMBL
    A0A8C0PQH0, A0A8I3NWY6, A0A8P0NMS2, A0A8P0PNE4
    Conserved Domains (2) summary
    pfam04598
    Location:4 → 238
    Gasdermin; Gasdermin family
    pfam17708
    Location:307 → 479
    Gasdermin_C; Gasdermin PUB domain

  7. XM_025450855.3 → XP_025306640.1  gasdermin-D isoform X1

    UniProtKB/TrEMBL
    A0A8C0PQH0, A0A8I3NWY6, A0A8P0NMS2, A0A8P0PNE4
    Conserved Domains (2) summary
    pfam04598
    Location:4 → 238
    Gasdermin; Gasdermin family
    pfam17708
    Location:307 → 479
    Gasdermin_C; Gasdermin PUB domain

  8. XM_049092845.1 → XP_048948802.1  gasdermin-D isoform X4

  9. XM_049092844.1 → XP_048948801.1  gasdermin-D isoform X3

    UniProtKB/TrEMBL
    A0A8C0L4Q4, A0A8C0SB41

  10. XM_049092841.1 → XP_048948798.1  gasdermin-D isoform X1

    UniProtKB/TrEMBL
    A0A8C0PQH0, A0A8P0NMS2
Nucleotide Protein
Heading Accession and Version

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