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FES FES proto-oncogene, tyrosine kinase [ Canis lupus dingo (dingo) ]

Gene ID: 112653511, updated on 15-Mar-2024

Summary

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Gene symbol
FES
Gene description
FES proto-oncogene, tyrosine kinase
See related
Ensembl:ENSCAFG00020016150
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
19
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 3 NC_064245.1 (53395465..53405130, complement)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 3 Unlocalized Scaffold NW_023365069.1 (54188131..54197832, complement)

Chromosome 3 - NC_064245.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene mannosidase alpha class 2A member 2 Neighboring gene furin, paired basic amino acid cleaving enzyme Neighboring gene uncharacterized LOC118354293

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mast cell degranulation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Fes/Fps

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064245.1 Reference ASM325472v2

    Range
    53395465..53405130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025437712.3 → XP_025293497.1  tyrosine-protein kinase Fes/Fps

    UniProtKB/TrEMBL
    A0A8C0KTR4, A0A8C0M251, A0A8C0RWB5, A0A8I3MKV4
    Related
    ENSCAFP00020020383.1
    Conserved Domains (3) summary
    cd10361
    Location:451 → 535
    SH2_Fps_family; Src homology 2 (SH2) domain found in feline sarcoma, Fujinami poultry sarcoma, and fes-related (Fes/Fps/Fer) proteins
    cd05084
    Location:562 → 813
    PTKc_Fes; Catalytic domain of the Protein Tyrosine Kinase, Fes
    cl12013
    Location:7 → 237
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
Nucleotide Protein
Heading Accession and Version

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