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SMG7 SMG7 nonsense mediated mRNA decay factor [ Canis lupus dingo (dingo) ]

Gene ID: 112648480, updated on 3-Apr-2024

Summary

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Gene symbol
SMG7
Gene description
SMG7 nonsense mediated mRNA decay factor
See related
Ensembl:ENSCAFG00020015475
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
25
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 7 NC_064249.1 (16514586..16607647)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 7 Unlocalized Scaffold NW_023365116.1 (17312893..17405920)

Chromosome 7 - NC_064249.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118355270 Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene uncharacterized LOC125755405 Neighboring gene uncharacterized LOC112648238 Neighboring gene neutrophil cytosolic factor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nonsense-mediated mRNA decay factor SMG7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064249.1 Reference ASM325472v2

    Range
    16514586..16607647
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035719179.2 → XP_035575072.1  nonsense-mediated mRNA decay factor SMG7 isoform X9

    UniProtKB/TrEMBL
    A0A8C0KPC2
    Conserved Domains (3) summary
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  2. XM_035719175.2 → XP_035575068.1  nonsense-mediated mRNA decay factor SMG7 isoform X8

    UniProtKB/TrEMBL
    A0A8C0KS08
    Conserved Domains (4) summary
    PRK10263
    Location:638 → 905
    PRK10263; DNA translocase FtsK; Provisional
    sd00006
    Location:136 → 162
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:153 → 413
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:37 → 149
    EST1; Telomerase activating protein Est1

  3. XM_025430044.3 → XP_025285829.1  nonsense-mediated mRNA decay factor SMG7 isoform X5

    UniProtKB/TrEMBL
    A0A8C0KS08
    Related
    ENSCAFP00020019493.1
    Conserved Domains (4) summary
    PRK10263
    Location:656 → 923
    PRK10263; DNA translocase FtsK; Provisional
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  4. XM_025430042.3 → XP_025285827.1  nonsense-mediated mRNA decay factor SMG7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KS08
    Conserved Domains (4) summary
    PRK10263
    Location:685 → 952
    PRK10263; DNA translocase FtsK; Provisional
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  5. XM_049112142.1 → XP_048968099.1  nonsense-mediated mRNA decay factor SMG7 isoform X3

  6. XM_049112143.1 → XP_048968100.1  nonsense-mediated mRNA decay factor SMG7 isoform X4

  7. XM_025430041.3 → XP_025285826.1  nonsense-mediated mRNA decay factor SMG7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0KS08
    Conserved Domains (4) summary
    PRK10263
    Location:695 → 962
    PRK10263; DNA translocase FtsK; Provisional
    sd00006
    Location:193 → 219
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:210 → 470
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:94 → 206
    EST1; Telomerase activating protein Est1

  8. XM_025430046.3 → XP_025285831.1  nonsense-mediated mRNA decay factor SMG7 isoform X7

    UniProtKB/TrEMBL
    A0A8C0KS89, A0A8I3MLD7, A0A8P0SZB7
    Related
    ENSCAFP00020019494.1
    Conserved Domains (3) summary
    sd00006
    Location:193 → 219
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:210 → 470
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:94 → 206
    EST1; Telomerase activating protein Est1

  9. XM_025430043.3 → XP_025285828.1  nonsense-mediated mRNA decay factor SMG7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KS08
    Conserved Domains (4) summary
    PRK10263
    Location:685 → 952
    PRK10263; DNA translocase FtsK; Provisional
    sd00006
    Location:183 → 209
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:200 → 460
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:84 → 196
    EST1; Telomerase activating protein Est1

  10. XM_025430045.3 → XP_025285830.1  nonsense-mediated mRNA decay factor SMG7 isoform X6

    UniProtKB/TrEMBL
    A0A8C0KPC2
    Related
    ENSCAFP00020019474.1
    Conserved Domains (3) summary
    sd00006
    Location:193 → 219
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:210 → 470
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:94 → 206
    EST1; Telomerase activating protein Est1

  11. XM_025430047.3 → XP_025285832.1  nonsense-mediated mRNA decay factor SMG7 isoform X10

    UniProtKB/TrEMBL
    A0A8C0KPC2
    Conserved Domains (3) summary
    sd00006
    Location:193 → 219
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:210 → 470
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:94 → 206
    EST1; Telomerase activating protein Est1

  12. XM_049112144.1 → XP_048968101.1  nonsense-mediated mRNA decay factor SMG7 isoform X8

Nucleotide Protein
Heading Accession and Version

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