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HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 [ Canis lupus dingo (dingo) ]

Gene ID: 112648344, updated on 15-Mar-2024

Summary

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Gene symbol
HSD11B1
Gene description
hydroxysteroid 11-beta dehydrogenase 1
See related
Ensembl:ENSCAFG00020013207
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 7
Exon count:
12
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 7 NC_064249.1 (8022865..8088373)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 7 Unlocalized Scaffold NW_023365116.1 (8803273..8868720)

Chromosome 7 - NC_064249.1Genomic Context describing neighboring genes Neighboring gene laminin subunit beta 3 Neighboring gene G0/G1 switch 2 Neighboring gene U6 spliceosomal RNA Neighboring gene TRAF3 interacting protein 3 Neighboring gene chromosome 7 C1orf74 homolog Neighboring gene interferon regulatory factor 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in steroid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
11-beta-hydroxysteroid dehydrogenase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064249.1 Reference ASM325472v2

    Range
    8022865..8088373
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025429810.3 → XP_025285595.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X3

    Conserved Domains (1) summary
    cd05332
    Location:2 → 250
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs

  2. XM_025429805.3 → XP_025285590.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KJ54, A0A8C0NKS2, A0A8I3MG39, A0A8P0NQU5, Q5XX84
    Conserved Domains (1) summary
    cd05332
    Location:32 → 280
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs

  3. XM_049112069.1 → XP_048968026.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X1

  4. XM_049112070.1 → XP_048968027.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X4

  5. XM_025429807.3 → XP_025285592.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KJ54, A0A8C0NKS2, A0A8I3MG39, A0A8P0NQU5, Q5XX84
    Conserved Domains (1) summary
    cd05332
    Location:32 → 280
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs

  6. XM_025429806.3 → XP_025285591.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KJ54, A0A8C0NKS2, A0A8I3MG39, A0A8P0NQU5, Q5XX84
    Conserved Domains (1) summary
    cd05332
    Location:32 → 280
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs

  7. XM_025429811.3 → XP_025285596.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X3

    Conserved Domains (1) summary
    cd05332
    Location:2 → 250
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs

  8. XM_025429808.3 → XP_025285593.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KJ54, A0A8C0NKS2, A0A8I3MG39, A0A8P0NQU5, Q5XX84
    Conserved Domains (1) summary
    cd05332
    Location:32 → 280
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs

  9. XM_035719287.2 → XP_035575180.1  11-beta-hydroxysteroid dehydrogenase 1 isoform X3

    Conserved Domains (1) summary
    cd05332
    Location:2 → 250
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
Nucleotide Protein
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