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GSR glutathione-disulfide reductase [ Canis lupus dingo (dingo) ]

Gene ID: 112642636, updated on 11-Apr-2024

Summary

Gene symbol
GSR
Gene description
glutathione-disulfide reductase
See related
Ensembl:ENSCAFG00020001065
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus dingo (sub-species: dingo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
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Genomic context

Location:
chromosome: 16
Exon count:
15
Annotation release Status Assembly Chr Location
102 current ASM325472v2 (GCF_003254725.2) 16 NC_064258.1 (34621059..34670748)
101 previous assembly UNSW_AlpineDingo_1.0 (GCF_012295265.1) 16 Unlocalized Scaffold NW_023365166.1 (35151841..35201200)

Chromosome 16 - NC_064258.1Genomic Context describing neighboring genes Neighboring gene RNA transcription, translation and transport factor protein-like Neighboring gene protein phosphatase 2 catalytic subunit beta Neighboring gene UBX domain protein 8 Neighboring gene uncharacterized LOC125752711 Neighboring gene uncharacterized LOC125752710 Neighboring gene transfer RNA aspartic acid (anticodon AUC) Neighboring gene 60S ribosomal protein L32-like Neighboring gene general transcription factor IIE subunit 2 Neighboring gene small integral membrane protein 18

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glutathione-disulfide reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to oxidative stress IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
glutathione reductase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus dingo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM325472v2

Genomic

  1. NC_064258.1 Reference ASM325472v2

    Range
    34621059..34670748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025420558.3XP_025276343.1  glutathione reductase, mitochondrial isoform X3

    UniProtKB/TrEMBL
    A0A8C0QTA8
    Related
    ENSCAFP00020001251.1
    Conserved Domains (1) summary
    cl39093
    Location:19438
    Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase
  2. XM_049095290.1XP_048951247.1  glutathione reductase, mitochondrial isoform X1

  3. XM_025420473.3XP_025276258.1  glutathione reductase, mitochondrial isoform X2

    UniProtKB/TrEMBL
    A0A8C0SRY7, A0A8C0SS74, A0A8I3NVE9, A0A8I3P561
    Related
    ENSCAFP00020001227.1
    Conserved Domains (1) summary
    TIGR01421
    Location:63521
    gluta_reduc_1; glutathione-disulfide reductase, animal/bacterial