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CISH cytokine inducible SH2 containing protein [ Theropithecus gelada (gelada) ]

Gene ID: 112618655, updated on 15-Mar-2024

Summary

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Gene symbol
CISH
Gene description
cytokine inducible SH2 containing protein
See related
Ensembl:ENSTGEG00000003642
Gene type
protein coding
RefSeq status
MODEL
Organism
Theropithecus gelada
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Theropithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
100 current Tgel_1.0 (GCF_003255815.1) 2 NC_037669.1 (89574709..89579862)

Chromosome 2 - NC_037669.1Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 3 Neighboring gene zinc finger protein 652 pseudogene Neighboring gene MAPK activated protein kinase 3 Neighboring gene chromosome 2 C3orf18 homolog Neighboring gene HemK methyltransferase family member 1 Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 2 Neighboring gene uncharacterized LOC112618244

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037669.1 Chromosome 2 Reference Tgel_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Theropithecus gelada Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Tgel_1.0 Primary Assembly

Genomic

  1. NC_037669.1 Reference Tgel_1.0 Primary Assembly

    Range
    89574709..89579862
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025375949.1 → XP_025231734.1  cytokine-inducible SH2-containing protein isoform X1

    Conserved Domains (2) summary
    cd10718
    Location:93 → 180
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:234 → 274
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...

  2. XM_025375950.1 → XP_025231735.1  cytokine-inducible SH2-containing protein isoform X2

    UniProtKB/TrEMBL
    A0A8D2EE19
    Related
    ENSTGEP00000004339.1, ENSTGET00000005281.1
    Conserved Domains (2) summary
    cd10718
    Location:77 → 164
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cd03734
    Location:218 → 258
    SOCS_CIS1; SOCS (suppressors of cytokine signaling) box of CIS (cytokine-inducible SH2 protein) 1-like proteins. Together with the SOCS proteins, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. ...
Nucleotide Protein
Heading Accession and Version

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