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DNAH12 dynein axonemal heavy chain 12 [ Desmodus rotundus (common vampire bat) ]

Gene ID: 112301142, updated on 30-Mar-2024

Summary

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Gene symbol
DNAH12
Gene description
dynein axonemal heavy chain 12
Gene type
protein coding
RefSeq status
MODEL
Organism
Desmodus rotundus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Desmodontinae; Desmodus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
76
Annotation release Status Assembly Chr Location
RS_2023_02 current HLdesRot8A (GCF_022682495.1) 8 NC_071394.1 (85727383..85946621)
101 previous assembly ASM294091v2 (GCF_002940915.1) Unplaced Scaffold NW_020091016.1 (14043978..14273757, complement)

Chromosome 8 - NC_071394.1Genomic Context describing neighboring genes Neighboring gene non-POU domain-containing octamer-binding protein-like Neighboring gene phosphodiesterase 12 Neighboring gene U6 spliceosomal RNA Neighboring gene ankyrin repeat and SOCS box containing 14 Neighboring gene adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dynein intermediate chain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dynein light intermediate chain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables minus-end-directed microtubule motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in microtubule-based movement IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of dynein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dynein axonemal heavy chain 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022682495.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HLdesRot8A Primary Assembly

Genomic

  1. NC_071394.1 Reference HLdesRot8A Primary Assembly

    Range
    85727383..85946621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045192339.2 → XP_045048274.1  dynein axonemal heavy chain 12 isoform X1

    Conserved Domains (7) summary
    COG5245
    Location:891 → 3595
    DYN1; Dynein, heavy chain [Cytoskeleton]
    PRK03918
    Location:474 → 766
    PRK03918; DNA double-strand break repair ATPase Rad50
    pfam08393
    Location:676 → 1110
    DHC_N2; Dynein heavy chain, N-terminal region 2
    pfam12774
    Location:1238 → 1564
    AAA_6; Hydrolytic ATP binding site of dynein motor region D1
    pfam12780
    Location:2246 → 2506
    AAA_8; P-loop containing dynein motor region D4
    pfam12781
    Location:2896 → 3112
    AAA_9; ATP-binding dynein motor region D5
    pfam18199
    Location:3656 → 3956
    Dynein_C; Dynein heavy chain C-terminal domain

  2. XM_053929996.1 → XP_053785971.1  dynein axonemal heavy chain 12 isoform X1

  3. XM_053929995.1 → XP_053785970.1  dynein axonemal heavy chain 12 isoform X1

  4. XM_045192340.2 → XP_045048275.1  dynein axonemal heavy chain 12 isoform X2

Nucleotide Protein
Heading Accession and Version

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