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LEP leptin [ Desmodus rotundus (common vampire bat) ]

Gene ID: 112299732, updated on 30-Mar-2024

Summary

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Gene symbol
LEP
Gene description
leptin
Gene type
protein coding
RefSeq status
MODEL
Organism
Desmodus rotundus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Desmodontinae; Desmodus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_02 current HLdesRot8A (GCF_022682495.1) 6 NC_071392.1 (74823348..74834941)
101 previous assembly ASM294091v2 (GCF_002940915.1) Unplaced Scaffold NW_020090872.1 (8303320..8314916)

Chromosome 6 - NC_071392.1Genomic Context describing neighboring genes Neighboring gene staphylococcal nuclease and tudor domain containing 1 Neighboring gene 60S ribosomal protein L23a-like Neighboring gene procathepsin L-like Neighboring gene RNA binding motif protein 28 Neighboring gene proline rich transmembrane protein 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptide hormone receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of protein kinase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in energy reserve metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of appetite by leptin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of TOR signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of p38MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to insulin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
leptin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022682495.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HLdesRot8A Primary Assembly

Genomic

  1. NC_071392.1 Reference HLdesRot8A Primary Assembly

    Range
    74823348..74834941
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045191176.2 → XP_045047111.2  leptin isoform X1

  2. XM_045191177.2 → XP_045047112.2  leptin isoform X2

  3. XM_024554946.3 → XP_024410714.2  leptin isoform X1

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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