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CREBBP CREB binding protein [ Desmodus rotundus (common vampire bat) ]

Gene ID: 112298356, updated on 30-Mar-2024

Summary

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Gene symbol
CREBBP
Gene description
CREB binding protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Desmodus rotundus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Desmodontinae; Desmodus
Orthologs
human mouse all
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Genomic context

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See CREBBP in Genome Data Viewer
Location:
chromosome: 1
Exon count:
31
Annotation release Status Assembly Chr Location
RS_2023_02 current HLdesRot8A (GCF_022682495.1) 1 NC_071387.1 (100917931..101051508, complement)
101 previous assembly ASM294091v2 (GCF_002940915.1) Unplaced Scaffold NW_020090761.1 (3566510..3701763, complement)

Chromosome 1 - NC_071387.1Genomic Context describing neighboring genes Neighboring gene splicing factor 3B subunit 6-like Neighboring gene deoxyribonuclease 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like 3 Neighboring gene TNF receptor associated protein 1 Neighboring gene tubulin alpha-1C chain-like Neighboring gene small nuclear ribonucleoprotein Sm D2-like Neighboring gene adenylate cyclase 9 Neighboring gene neo-calmodulin-like Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CREB-binding protein
Names
Putative histone acetylation protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022682495.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HLdesRot8A Primary Assembly

Genomic

  1. NC_071387.1 Reference HLdesRot8A Primary Assembly

    Range
    100917931..101051508 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024553300.3 → XP_024409068.1  CREB-binding protein

    UniProtKB/TrEMBL
    K9J4E6
    Conserved Domains (10) summary
    cd05495
    Location:1086 → 1193
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    cd02337
    Location:1704 → 1744
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    cd15802
    Location:1205 → 1277
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15557
    Location:1279 → 1310
    PHD_CBP_p300; PHD finger found in CREB-binding protein (CBP) and histone acetyltransferase p300
    pfam02172
    Location:586 → 666
    KIX; KIX domain
    pfam02135
    Location:362 → 429
    zf-TAZ; TAZ zinc finger
    pfam08214
    Location:1341 → 1648
    HAT_KAT11; Histone acetylation protein
    pfam09030
    Location:2033 → 2112
    Creb_binding; Creb binding
    pfam09606
    Location:1959 → 2406
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl26464
    Location:613 → 1049
    Atrophin-1; Atrophin-1 family
Nucleotide Protein
Heading Accession and Version

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