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si:dkey-91m11.5 BCR activator of RhoGEF and GTPase [ Oryzias melastigma (Indian medaka) ]

Gene ID: 112148870, updated on 15-Mar-2024

Summary

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Gene symbol
si:dkey-91m11.5
Gene description
BCR activator of RhoGEF and GTPase
See related
Ensembl:ENSOMEG00000021614
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryzias melastigma
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae; Oryzias
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: LG9
Exon count:
24
Annotation release Status Assembly LG Location
101 current ASM292280v2 (GCF_002922805.2) LG9 NC_050520.1 (30592688..30637992, complement)
100 previous assembly Om_v0.7.RACA (GCF_002922805.1) Unplaced Scaffold NW_020096084.1 (2968595..3013899)

Linkage Group LG9 - NC_050520.1Genomic Context describing neighboring genes Neighboring gene adenosine A2a receptor a Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1-like a Neighboring gene intraflagellar transport 81 homolog Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2a Neighboring gene anaphase promoting complex subunit 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Tissue-specific transcriptome assemblies of the marine medaka Oryzias melastigma and comparative analysis with the freshwater medaka Oryzias latipes. Lai KP, et al. BMC Genomics, 2015 Feb 27. PMID 25765076, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein
Names
BCR, RhoGEF and GTPase activating protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oryzias melastigma Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM292280v2 Primary Assembly

Genomic

  1. NC_050520.1 Reference ASM292280v2 Primary Assembly

    Range
    30592688..30637992 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024276268.1 → XP_024132036.1  PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein

    UniProtKB/TrEMBL
    A0A3B3CQ95, A0A3B3CR36
    Related
    ENSOMEP00000019790.1, ENSOMET00000029116.1
    Conserved Domains (5) summary
    cd08686
    Location:932 → 1052
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd00160
    Location:519 → 709
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd04387
    Location:1071 → 1270
    RhoGAP_Bcr; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, a Ser/Thr ...
    pfam09036
    Location:3 → 75
    Bcr-Abl_Oligo; Bcr-Abl oncoprotein oligomerization domain
    cl17171
    Location:704 → 896
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein Strain
Heading Accession and Version

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Molecular Biology Databases