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NGEF neuronal guanine nucleotide exchange factor [ Terrapene carolina triunguis (Three-toed box turtle) ]

Gene ID: 112118504, updated on 15-Mar-2024

Summary

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Gene symbol
NGEF
Gene description
neuronal guanine nucleotide exchange factor
See related
Ensembl:ENSTMTG00000002134
Gene type
protein coding
RefSeq status
MODEL
Organism
Terrapene carolina triunguis (sub-species: triunguis)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Terrapene
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
102 current T_m_triunguis-2.0 (GCF_002925995.2) Unplaced Scaffold NW_020664439.1 (2239450..2335485, complement)
100 previous assembly T_m_triunguis-1.0 (GCF_002925995.1) Unplaced Scaffold NW_019962881.1 (3279034..3327952)

NW_020664439.1Genomic Context describing neighboring genes Neighboring gene GRB10 interacting GYF protein 2 Neighboring gene potassium inwardly rectifying channel subfamily J member 13 Neighboring gene secondary ossification center associated regulator of chondrocyte maturation Neighboring gene neuraminidase 2 Neighboring gene inositol polyphosphate-5-phosphatase D

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephexin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Terrapene carolina triunguis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T_m_triunguis-2.0

Genomic

  1. NW_020664439.1 Reference T_m_triunguis-2.0

    Range
    2239450..2335485 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026650115.1 → XP_026505900.1  ephexin-1

    UniProtKB/TrEMBL
    A0A674I4F3
    Related
    ENSTMTP00000002767.1, ENSTMTT00000002874.1
    Conserved Domains (3) summary
    cd11939
    Location:684 → 738
    SH3_ephexin1; Src homology 3 domain of the Rho guanine nucleotide exchange factor, ephexin-1 (also called NGEF or ARHGEF27)
    cd01221
    Location:545 → 671
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain
    pfam00621
    Location:345 → 523
    RhoGEF; RhoGEF domain

  2. XM_026650113.1 → XP_026505898.1  ephexin-1

    UniProtKB/TrEMBL
    A0A674I4F3
    Conserved Domains (3) summary
    cd11939
    Location:684 → 738
    SH3_ephexin1; Src homology 3 domain of the Rho guanine nucleotide exchange factor, ephexin-1 (also called NGEF or ARHGEF27)
    cd01221
    Location:545 → 671
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain
    pfam00621
    Location:345 → 523
    RhoGEF; RhoGEF domain
Nucleotide Protein
Heading Accession and Version

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