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UPF2 UPF2 regulator of nonsense mediated mRNA decay [ Terrapene carolina triunguis (Three-toed box turtle) ]

Gene ID: 112114249, updated on 15-Mar-2024

Summary

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Gene symbol
UPF2
Gene description
UPF2 regulator of nonsense mediated mRNA decay
See related
Ensembl:ENSTMTG00000011388
Gene type
protein coding
RefSeq status
MODEL
Organism
Terrapene carolina triunguis (sub-species: triunguis)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Terrapene
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current T_m_triunguis-2.0 (GCF_002925995.2) Unplaced Scaffold NW_020664419.1 (9422046..9551858, complement)
100 previous assembly T_m_triunguis-1.0 (GCF_002925995.1) Unplaced Scaffold NW_019961705.1 (100825..228741)

NW_020664419.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115271174 Neighboring gene proline and serine rich 2 Neighboring gene dehydrogenase E1 and transketolase domain containing 1 Neighboring gene SEC61 translocon subunit alpha 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of exon-exon junction complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
regulator of nonsense transcripts 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Terrapene carolina triunguis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T_m_triunguis-2.0

Genomic

  1. NW_020664419.1 Reference T_m_triunguis-2.0

    Range
    9422046..9551858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024210862.2 → XP_024066630.1  regulator of nonsense transcripts 2 isoform X4

    UniProtKB/TrEMBL
    A0A674J1C1, A0A674J4U0
    Related
    ENSTMTP00000015553.1, ENSTMTT00000016107.1
    Conserved Domains (4) summary
    smart00543
    Location:796 → 1009
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    COG5271
    Location:461 → 625
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    pfam04050
    Location:1118 → 1241
    Upf2; Up-frameshift suppressor 2
    cl19727
    Location:357 → 420
    DUF1451; Zinc-ribbon containing domain

  2. XM_024210863.2 → XP_024066631.1  regulator of nonsense transcripts 2 isoform X4

    UniProtKB/TrEMBL
    A0A674J1C1, A0A674J4U0
    Conserved Domains (4) summary
    smart00543
    Location:796 → 1009
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    COG5271
    Location:461 → 625
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    pfam04050
    Location:1118 → 1241
    Upf2; Up-frameshift suppressor 2
    cl19727
    Location:357 → 420
    DUF1451; Zinc-ribbon containing domain

  3. XM_029910843.1 → XP_029766703.1  regulator of nonsense transcripts 2 isoform X1

    UniProtKB/TrEMBL
    A0A674J1C1
    Conserved Domains (4) summary
    smart00543
    Location:825 → 1038
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    COG5271
    Location:490 → 654
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    pfam04050
    Location:1147 → 1270
    Upf2; Up-frameshift suppressor 2
    cl19727
    Location:386 → 449
    DUF1451; Zinc-ribbon containing domain

  4. XM_024210860.3 → XP_024066628.1  regulator of nonsense transcripts 2 isoform X2

    UniProtKB/TrEMBL
    A0A674J1C1
    Conserved Domains (3) summary
    smart00543
    Location:801 → 1014
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1123 → 1246
    Upf2; Up-frameshift suppressor 2
    cl19727
    Location:386 → 449
    DUF1451; Zinc-ribbon containing domain

  5. XM_024210864.3 → XP_024066632.1  regulator of nonsense transcripts 2 isoform X4

    UniProtKB/TrEMBL
    A0A674J1C1, A0A674J4U0
    Conserved Domains (4) summary
    smart00543
    Location:796 → 1009
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    COG5271
    Location:461 → 625
    MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    pfam04050
    Location:1118 → 1241
    Upf2; Up-frameshift suppressor 2
    cl19727
    Location:357 → 420
    DUF1451; Zinc-ribbon containing domain

  6. XM_024210861.3 → XP_024066629.1  regulator of nonsense transcripts 2 isoform X3

    UniProtKB/TrEMBL
    A0A674J1C1
    Conserved Domains (3) summary
    smart00543
    Location:801 → 1014
    MIF4G; Middle domain of eukaryotic initiation factor 4G (eIF4G)
    pfam04050
    Location:1123 → 1246
    Upf2; Up-frameshift suppressor 2
    cl19727
    Location:386 → 449
    DUF1451; Zinc-ribbon containing domain
Nucleotide Protein
Heading Accession and Version

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