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TWNK twinkle mtDNA helicase [ Terrapene carolina triunguis (Three-toed box turtle) ]

Gene ID: 112111048, updated on 15-Mar-2024

Summary

Gene symbol
TWNK
Gene description
twinkle mtDNA helicase
See related
Ensembl:ENSTMTG00000002956
Gene type
protein coding
RefSeq status
MODEL
Organism
Terrapene carolina triunguis (sub-species: triunguis)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Emydidae; Terrapene
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
6
Annotation release Status Assembly Chr Location
102 current T_m_triunguis-2.0 (GCF_002925995.2) Unplaced Scaffold NW_020664446.1 (3380122..3394840, complement)
100 previous assembly T_m_triunguis-1.0 (GCF_002925995.1) Unplaced Scaffold NW_019960860.1 (511062..525733, complement)

NW_020664446.1Genomic Context describing neighboring genes Neighboring gene PDZ domain containing 7 Neighboring gene leucine zipper tumor suppressor 2 Neighboring gene mitochondrial ribosomal protein L43 Neighboring gene semaphorin 4G

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrial DNA replication IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
twinkle protein, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Terrapene carolina triunguis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T_m_triunguis-2.0

Genomic

  1. NW_020664446.1 Reference T_m_triunguis-2.0

    Range
    3380122..3394840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024206314.3XP_024062082.2  twinkle protein, mitochondrial isoform X1

    UniProtKB/TrEMBL
    A0A674I878
    Related
    ENSTMTP00000004027.1, ENSTMTT00000004168.1
    Conserved Domains (2) summary
    cd01029
    Location:260336
    TOPRIM_primases; The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG type primases are ...
    cd01122
    Location:375632
    GP4d_helicase; GP4d_helicase is a homohexameric 5'-3' helicases. Helicases couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands.
  2. XM_024206315.3XP_024062083.1  twinkle protein, mitochondrial isoform X2

    Conserved Domains (1) summary
    cl38936
    Location:3198
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases