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FAM107A family with sequence similarity 107 member A [ Homo sapiens (human) ]

Gene ID: 11170, updated on 8-May-2016
Official Symbol
FAM107Aprovided by HGNC
Official Full Name
family with sequence similarity 107 member Aprovided by HGNC
Primary source
HGNC:HGNC:30827
See related
Ensembl:ENSG00000168309 HPRD:09753; MIM:608295; Vega:OTTHUMG00000159159
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DRR1; TU3A
Orthologs
Location:
3p21.1
Exon count:
8
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 3 NC_000003.12 (58564112..58627610, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (58549841..58613337, complement)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene potassium channel tetramerization domain containing 6 Neighboring gene ribosomal protein L27 pseudogene 9 Neighboring gene acyl-CoA oxidase 2, branched chain Neighboring gene uncharacterized LOC105377107 Neighboring gene FAM3D antisense RNA 1 Neighboring gene uncharacterized LOC105377109 Neighboring gene family with sequence similarity 3 member D Neighboring gene chromosome 3 open reading frame 67 Neighboring gene C3orf67 antisense RNA 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ30158, FLJ45473

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
regulation of cell growth IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
neuron projection IEA
Inferred from Electronic Annotation
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
protein FAM107A
Names
down-regulated in renal cell carcinoma 1
family with sequence similarity 107, member A

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076778.2NP_001070246.1  protein FAM107A isoform a

    See identical proteins and their annotated locations for NP_001070246.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
    Source sequence(s)
    AF035283, AF089853, AL050264, BM980503, BX645008, EU569833
    Consensus CDS
    CCDS2892.1
    UniProtKB/Swiss-Prot
    O95990
    UniProtKB/TrEMBL
    Q6IAM1
    Related
    ENSP00000354270, OTTHUMP00000214215, ENST00000360997, OTTHUMT00000353583
    Conserved Domains (1) summary
    pfam06625
    Location:16133
    DUF1151; Protein of unknown function (DUF1151)
  2. NM_001282713.1NP_001269642.1  protein FAM107A isoform b

    See identical proteins and their annotated locations for NP_001269642.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (b) has a longer N-terminus, compared to isoform a.
    Source sequence(s)
    AC119424, AF089853, BM980503, DB486334, EU569833
    Consensus CDS
    CCDS63672.1
    UniProtKB/Swiss-Prot
    O95990
    UniProtKB/TrEMBL
    Q6IAM1
    Related
    ENSP00000400858, OTTHUMP00000214216, ENST00000447756, OTTHUMT00000353584
    Conserved Domains (1) summary
    pfam06625
    Location:44161
    DUF1151; Protein of unknown function (DUF1151)
  3. NM_001282714.1NP_001269643.1  protein FAM107A isoform c

    See identical proteins and their annotated locations for NP_001269643.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (c) has a longer N-terminus, compared to isoform a.
    Source sequence(s)
    AF089853, BM980503, DA277819, DT216507, EU569833
    Consensus CDS
    CCDS63673.1
    UniProtKB/Swiss-Prot
    O95990
    UniProtKB/TrEMBL
    A0A024R327, Q6IAM1
    Related
    ENSP00000419124, OTTHUMP00000214214, ENST00000474531, OTTHUMT00000353582
    Conserved Domains (1) summary
    pfam06625
    Location:47164
    DUF1151; Protein of unknown function (DUF1151)
  4. NM_007177.3NP_009108.1  protein FAM107A isoform a

    See identical proteins and their annotated locations for NP_009108.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the shortest isoform (a). Both variants 1 and 2 encode the same isoform.
    Source sequence(s)
    AF035283, AF089853, BC010561, BM980503, BX645008, EU569833
    Consensus CDS
    CCDS2892.1
    UniProtKB/Swiss-Prot
    O95990
    UniProtKB/TrEMBL
    Q6IAM1
    Related
    ENSP00000377991, OTTHUMP00000214217, ENST00000394481, OTTHUMT00000353585
    Conserved Domains (1) summary
    pfam06625
    Location:16133
    DUF1151; Protein of unknown function (DUF1151)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p2 Primary Assembly

    Range
    58564112..58627610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005264835.2XP_005264892.1  

    See identical proteins and their annotated locations for XP_005264892.1

    UniProtKB/Swiss-Prot
    O95990
    UniProtKB/TrEMBL
    Q6IAM1
    Conserved Domains (1) summary
    pfam06625
    Location:16133
    DUF1151; Protein of unknown function (DUF1151)

Alternate CHM1_1.1

Genomic

  1. NC_018914.2 Alternate CHM1_1.1

    Range
    58499971..58563466 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)