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TLE5 TLE family member 5, transcriptional modulator [ Felis catus (domestic cat) ]

Gene ID: 111556319, updated on 15-Mar-2024

Summary

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Gene symbol
TLE5
Gene description
TLE family member 5, transcriptional modulator
See related
EnsemblRapid:ENSFCTG00005032905
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Also known as
AES
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: A2
Exon count:
7
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A2 NC_058369.1 (2360013..2368581, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A2 NC_018724.3 (2419735..2428277, complement)

Chromosome A2 - NC_058369.1Genomic Context describing neighboring genes Neighboring gene TLE family member 2, transcriptional corepressor Neighboring gene uncharacterized LOC123381695 Neighboring gene G protein subunit alpha 11 Neighboring gene uncharacterized LOC123381704 Neighboring gene proline-rich receptor-like protein kinase PERK9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sequencing and comparative genomic analysis of 1227 Felis catus cDNA sequences enriched for developmental, clinical and nutritional phenotypes. Irizarry KJ, et al. BMC Genomics, 2012 Jan 18. PMID 22257742, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TLE family member 5
Names
amino-terminal enhancer of split

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058369.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    2360013..2368581 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045043396.1 → XP_044899331.1  TLE family member 5 isoform X3

  2. XM_023243612.2 → XP_023099380.1  TLE family member 5 isoform X2

    UniProtKB/TrEMBL
    A0A337SM34
    Conserved Domains (1) summary
    pfam03920
    Location:2 → 131
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  3. XM_023243608.2 → XP_023099376.1  TLE family member 5 isoform X1

    UniProtKB/TrEMBL
    A0A337SM34
    Related
    ENSFCTP00005060783.1, ENSFCTT00005090810.1
    Conserved Domains (1) summary
    pfam03920
    Location:2 → 132
    TLE_N; Groucho/TLE N-terminal Q-rich domain
Nucleotide Protein
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