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HPN hepsin [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

Gene ID: 111529944, updated on 15-Mar-2024

Summary

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Gene symbol
HPN
Gene description
hepsin
Gene type
protein coding
RefSeq status
MODEL
Organism
Piliocolobus tephrosceles
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
Orthologs
human mouse all
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Genomic context

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See HPN in Genome Data Viewer
Location:
chromosome: 21
Exon count:
8
Annotation release Status Assembly Chr Location
102 current ASM277652v3 (GCF_002776525.3) 21 NC_045454.1 (22315903..22331788, complement)
100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019321714.1 (750652..775865, complement)

Chromosome 21 - NC_045454.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat LGI family member 4 Neighboring gene FXYD domain containing ion transport regulator 1 Neighboring gene FXYD domain containing ion transport regulator 3 Neighboring gene sodium voltage-gated channel beta subunit 1 Neighboring gene GRAM domain containing 1A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of epithelial to mesenchymal transition IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine protease hepsin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM277652v3

Genomic

  1. NC_045454.1 Reference ASM277652v3

    Range
    22315903..22331788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_026448765.1 → XP_026304550.1  serine protease hepsin

    Conserved Domains (1) summary
    cd00190
    Location:66 → 199
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein
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