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CDC14A cell division cycle 14A [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

Gene ID: 111525745, updated on 15-Mar-2024

Summary

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Gene symbol
CDC14A
Gene description
cell division cycle 14A
See related
Ensembl:ENSPTEG00000024632
Gene type
protein coding
RefSeq status
MODEL
Organism
Piliocolobus tephrosceles
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
102 current ASM277652v3 (GCF_002776525.3) 1 NC_045434.1 (120951559..121121171, complement)
100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019318502.1 (1923972..2093575, complement)

Chromosome 1 - NC_045434.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L36a-like Neighboring gene G protein-coupled receptor 88 Neighboring gene 60S ribosomal protein L6 pseudogene Neighboring gene pre-mRNA-splicing factor SPF27 pseudogene Neighboring gene keratinocyte-associated transmembrane protein 2 pseudogene Neighboring gene RNA 3'-terminal phosphate cyclase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine/serine/threonine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of exit from mitosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitotic spindle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dual specificity protein phosphatase CDC14A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM277652v3

Genomic

  1. NC_045434.1 Reference ASM277652v3

    Range
    120951559..121121171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023191294.2 → XP_023047062.1  dual specificity protein phosphatase CDC14A isoform X2

    UniProtKB/TrEMBL
    A0A8C9HN48, A0A8C9LRU1
    Related
    ENSPTEP00000024057.1, ENSPTET00000034286.1
    Conserved Domains (3) summary
    pfam14671
    Location:16 → 152
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl02571
    Location:419 → 594
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cl21483
    Location:187 → 326
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  2. XM_023191296.3 → XP_023047064.1  dual specificity protein phosphatase CDC14A isoform X4

    UniProtKB/TrEMBL
    A0A8C9HN48
    Conserved Domains (2) summary
    pfam14671
    Location:16 → 152
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:187 → 326
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  3. XM_023191293.3 → XP_023047061.1  dual specificity protein phosphatase CDC14A isoform X1

    UniProtKB/TrEMBL
    A0A8C9HN48
    Related
    ENSPTEP00000024063.1
    Conserved Domains (3) summary
    pfam04388
    Location:465 → 603
    Hamartin; Hamartin protein
    pfam14671
    Location:16 → 152
    DSPn; Dual specificity protein phosphatase, N-terminal half
    cl21483
    Location:187 → 326
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

  4. XM_023191295.2 → XP_023047063.1  dual specificity protein phosphatase CDC14A isoform X3

    Conserved Domains (1) summary
    pfam04388
    Location:172 → 310
    Hamartin; Hamartin protein
Nucleotide Protein
Heading Accession and Version

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