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TNF tumor necrosis factor [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

Gene ID: 111523940, updated on 15-Mar-2024

Summary

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Gene symbol
TNF
Gene description
tumor necrosis factor
See related
Ensembl:ENSPTEG00000036173
Gene type
protein coding
RefSeq status
MODEL
Organism
Piliocolobus tephrosceles
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
102 current ASM277652v3 (GCF_002776525.3) 5 NC_045438.1 (136321804..136324643)
100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019318178.1 (421439..424308, complement)

Chromosome 5 - NC_045438.1Genomic Context describing neighboring genes Neighboring gene DExD-box helicase 39B Neighboring gene ATPase H+ transporting V1 subunit G2 Neighboring gene NFKB inhibitor like 1 Neighboring gene 40S ribosomal protein S11-like Neighboring gene lymphotoxin alpha Neighboring gene lymphotoxin beta Neighboring gene leukocyte specific transcript 1 Neighboring gene natural cytotoxicity triggering receptor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CD40 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM277652v3

Genomic

  1. NC_045438.1 Reference ASM277652v3

    Range
    136321804..136324643
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023188908.3 → XP_023044676.1  tumor necrosis factor

    UniProtKB/TrEMBL
    A0A8C9IM56
    Related
    ENSPTEP00000039013.1
    Conserved Domains (1) summary
    pfam00229
    Location:102 → 233
    TNF; TNF(tumor Necrosis Factor) family
Nucleotide Protein
Heading Accession and Version

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