U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ADAM8 ADAM metallopeptidase domain 8 [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

Gene ID: 111522061, updated on 15-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
ADAM8
Gene description
ADAM metallopeptidase domain 8
See related
Ensembl:ENSPTEG00000025411
Gene type
protein coding
RefSeq status
MODEL
Organism
Piliocolobus tephrosceles
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 9
Exon count:
24
Annotation release Status Assembly Chr Location
102 current ASM277652v3 (GCF_002776525.3) 9 NC_045442.1 (670396..684212)
100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019318099.1 (405712..419536)

Chromosome 9 - NC_045442.1Genomic Context describing neighboring genes Neighboring gene calcyon neuron specific vesicular protein Neighboring gene zinc finger protein 511 Neighboring gene tubulin gamma complex component 2 Neighboring gene uncharacterized LOC111522048 Neighboring gene VENT homeobox

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cellular extravasation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
disintegrin and metalloproteinase domain-containing protein 8

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM277652v3

Genomic

  1. NC_045442.1 Reference ASM277652v3

    Range
    670396..684212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023185813.2 → XP_023041581.1  disintegrin and metalloproteinase domain-containing protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A8C9LSA0
    Related
    ENSPTEP00000025053.1, ENSPTET00000035529.1
    Conserved Domains (5) summary
    smart00050
    Location:417 → 491
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:494 → 606
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:200 → 400
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:30 → 155
    Pep_M12B_propep; Reprolysin family propeptide
    cl27975
    Location:675 → 824
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)

  2. XM_023185815.3 → XP_023041583.1  disintegrin and metalloproteinase domain-containing protein 8 isoform X3

    UniProtKB/TrEMBL
    A0A8C9HQB7
    Related
    ENSPTEP00000025059.1
    Conserved Domains (4) summary
    smart00050
    Location:417 → 491
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:494 → 606
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:200 → 400
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:30 → 155
    Pep_M12B_propep; Reprolysin family propeptide

  3. XM_023185812.2 → XP_023041580.1  disintegrin and metalloproteinase domain-containing protein 8 isoform X1

    UniProtKB/TrEMBL
    A0A8C9I2D6
    Conserved Domains (5) summary
    smart00050
    Location:443 → 517
    DISIN; Homologues of snake disintegrins
    smart00608
    Location:520 → 632
    ACR; ADAM Cysteine-Rich Domain
    pfam01421
    Location:226 → 426
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:128 → 181
    Pep_M12B_propep; Reprolysin family propeptide
    cl27975
    Location:701 → 850
    EBV-NA3; Epstein-Barr virus nuclear antigen 3 (EBNA-3)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.