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CHRNA4 cholinergic receptor nicotinic alpha 4 subunit [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111186740, updated on 15-Mar-2024

Summary

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Gene symbol
CHRNA4
Gene description
cholinergic receptor nicotinic alpha 4 subunit
See related
Ensembl:ENSDLEG00000006419
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098028.1 (658127..680473)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160913.1 (659109..683516)

NW_022098028.1Genomic Context describing neighboring genes Neighboring gene eukaryotic translation elongation factor 1 alpha 2 Neighboring gene potassium voltage-gated channel subfamily Q member 2 Neighboring gene collagen type XX alpha 1 chain Neighboring gene ADP ribosylation factor GTPase activating protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neuronal acetylcholine receptor subunit alpha-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098028.1 Reference ASM228892v3 Primary Assembly

    Range
    658127..680473
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030762861.1 → XP_030618721.1  neuronal acetylcholine receptor subunit alpha-4 isoform X3

    UniProtKB/TrEMBL
    A0A7F8K7E4
    Conserved Domains (4) summary
    PHA03247
    Location:271 → 534
    PHA03247; large tegument protein UL36; Provisional
    TIGR00860
    Location:2 → 322
    LIC; Cation transporter family protein
    cd03558
    Location:80 → 94
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 161
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))

  2. XM_022597597.2 → XP_022453305.1  neuronal acetylcholine receptor subunit alpha-4 isoform X2

    UniProtKB/TrEMBL
    A0A2Y9Q6T1
    Related
    ENSDLEP00000008764.1, ENSDLET00000009677.1
    Conserved Domains (3) summary
    pfam02931
    Location:235 → 441
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:448 → 805
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    cl26386
    Location:621 → 757
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  3. XM_022597596.2 → XP_022453304.1  neuronal acetylcholine receptor subunit alpha-4 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9Q2G7
    Conserved Domains (3) summary
    pfam02931
    Location:235 → 441
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:448 → 620
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
    cl25756
    Location:575 → 762
    BASP1; Brain acid soluble protein 1 (BASP1 protein)
Nucleotide Protein
Heading Accession and Version

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