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RANGRF RAN guanine nucleotide release factor [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111185787, updated on 15-Mar-2024

Summary

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Gene symbol
RANGRF
Gene description
RAN guanine nucleotide release factor
See related
Ensembl:ENSDLEG00000021772
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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See RANGRF in Genome Data Viewer
Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098035.1 (11476033..11477468)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160909.1 (11403897..11405339)

NW_022098035.1Genomic Context describing neighboring genes Neighboring gene CST telomere replication complex component 1 Neighboring gene phosphoribosylformylglycinamidine synthase Neighboring gene solute carrier family 25 member 35 Neighboring gene Rho guanine nucleotide exchange factor 15 Neighboring gene KRAB-A domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sodium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heart contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane depolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ran guanine nucleotide release factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098035.1 Reference ASM228892v3 Primary Assembly

    Range
    11476033..11477468
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022595696.2 → XP_022451404.1  ran guanine nucleotide release factor isoform X2

    UniProtKB/TrEMBL
    A0A2Y9PX70
    Conserved Domains (1) summary
    cd00224
    Location:8 → 177
    Mog1; homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP)

  2. XM_022595698.2 → XP_022451406.1  ran guanine nucleotide release factor isoform X3

    UniProtKB/TrEMBL
    A0A2Y9Q1R7
    Conserved Domains (1) summary
    cl00169
    Location:8 → 117
    Mog1; homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP)

  3. XM_022595695.2 → XP_022451403.1  ran guanine nucleotide release factor isoform X1

    UniProtKB/TrEMBL
    A0A2Y9Q7G6
    Related
    ENSDLEP00000030590.1, ENSDLET00000033595.1
    Conserved Domains (1) summary
    cd00224
    Location:8 → 184
    Mog1; homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP)
Nucleotide Protein
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