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VEGFA vascular endothelial growth factor A [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111178866, updated on 15-Mar-2024

Summary

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Gene symbol
VEGFA
Gene description
vascular endothelial growth factor A
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098000.1 (15019162..15037655)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160881.1 (15019727..15038221)

NW_022098000.1Genomic Context describing neighboring genes Neighboring gene MAD2L1 binding protein Neighboring gene radial spoke head component 9 Neighboring gene mitochondrial ribosomal protein S18A Neighboring gene uncharacterized protein C6orf223 Neighboring gene mitochondrial ribosomal protein L14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemoattractant activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables heparin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vascular endothelial growth factor receptor 1 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables vascular endothelial growth factor receptor 2 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in induction of positive chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of endothelial cell proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of mast cell chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vascular endothelial growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vascular endothelial growth factor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
vascular endothelial growth factor A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098000.1 Reference ASM228892v3 Primary Assembly

    Range
    15019162..15037655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022582006.2 → XP_022437714.1  vascular endothelial growth factor A isoform X1

    UniProtKB/TrEMBL
    A0A2Y9NRE7
    Conserved Domains (2) summary
    smart00141
    Location:49 → 131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:166 → 214
    VEGF_C; VEGF heparin-binding domain

  2. XM_022582007.2 → XP_022437715.1  vascular endothelial growth factor A isoform X2

    UniProtKB/TrEMBL
    A0A2Y9NUK4
    Conserved Domains (2) summary
    smart00141
    Location:49 → 131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:160 → 208
    VEGF_C; VEGF heparin-binding domain

  3. XM_022582008.2 → XP_022437716.1  vascular endothelial growth factor A isoform X3

    UniProtKB/TrEMBL
    A0A2Y9NXQ3
    Conserved Domains (2) summary
    smart00141
    Location:49 → 131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    pfam14554
    Location:142 → 190
    VEGF_C; VEGF heparin-binding domain

  4. XM_022582009.2 → XP_022437717.1  vascular endothelial growth factor A isoform X4

    UniProtKB/TrEMBL
    A0A2Y9P341
    Conserved Domains (1) summary
    smart00141
    Location:49 → 131
    PDGF; Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
Nucleotide Protein
Heading Accession and Version

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