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DGKH diacylglycerol kinase eta [ Delphinapterus leucas (beluga whale) ]

Gene ID: 111175359, updated on 15-Mar-2024

Summary

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Gene symbol
DGKH
Gene description
diacylglycerol kinase eta
See related
Ensembl:ENSDLEG00000007260
Gene type
protein coding
RefSeq status
MODEL
Organism
Delphinapterus leucas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Monodontidae; Delphinapterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
33
Annotation release Status Assembly Chr Location
101 current ASM228892v3 (GCF_002288925.2) Unplaced Scaffold NW_022098021.1 (24291949..24472833, complement)
100 previous assembly ASM228892v2 (GCF_002288925.1) Unplaced Scaffold NW_019160869.1 (24298824..24479707, complement)

NW_022098021.1Genomic Context describing neighboring genes Neighboring gene TNF superfamily member 11 Neighboring gene A-kinase anchoring protein 11 Neighboring gene small nucleolar RNA SNORA43 Neighboring gene von Willebrand factor A domain containing 8 Neighboring gene 60S ribosomal protein L17 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase eta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Delphinapterus leucas Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM228892v3 Primary Assembly

Genomic

  1. NW_022098021.1 Reference ASM228892v3 Primary Assembly

    Range
    24291949..24472833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_022574920.2 → XP_022430628.1  diacylglycerol kinase eta isoform X3

    UniProtKB/TrEMBL
    A0A2Y9NMS3
    Conserved Domains (5) summary
    smart00109
    Location:279 → 324
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    smart00045
    Location:799 → 956
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:365 → 487
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:207 → 256
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd13274
    Location:98 → 194
    PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain

  2. XM_022574921.2 → XP_022430629.1  diacylglycerol kinase eta isoform X4

    UniProtKB/TrEMBL
    A0A2Y9N7B8
    Conserved Domains (2) summary
    smart00045
    Location:523 → 680
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:89 → 211
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)

  3. XM_022574919.1 → XP_022430627.1  diacylglycerol kinase eta isoform X2

    UniProtKB/TrEMBL
    A0A2Y9NGN9
    Conserved Domains (6) summary
    smart00109
    Location:248 → 293
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    smart00045
    Location:786 → 943
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:352 → 474
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:176 → 225
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd13274
    Location:67 → 163
    PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain
    cl15755
    Location:1164 → 1227
    SAM_superfamily; SAM (Sterile alpha motif )

  4. XM_022574918.1 → XP_022430626.1  diacylglycerol kinase eta isoform X2

    UniProtKB/TrEMBL
    A0A2Y9NGN9
    Related
    ENSDLEP00000009975.1, ENSDLET00000011025.1
    Conserved Domains (6) summary
    smart00109
    Location:248 → 293
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    smart00045
    Location:786 → 943
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:352 → 474
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:176 → 225
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd13274
    Location:67 → 163
    PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain
    cl15755
    Location:1164 → 1227
    SAM_superfamily; SAM (Sterile alpha motif )

  5. XM_022574917.1 → XP_022430625.1  diacylglycerol kinase eta isoform X1

    UniProtKB/TrEMBL
    A0A2Y9N8P7
    Related
    ENSDLEP00000009990.1, ENSDLET00000011040.1
    Conserved Domains (6) summary
    smart00109
    Location:279 → 324
    C1; Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains)
    smart00045
    Location:799 → 956
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:365 → 487
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:207 → 256
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd13274
    Location:98 → 194
    PH_DGK_type2; Type 2 Diacylglycerol kinase Pleckstrin homology (PH) domain
    cl15755
    Location:1177 → 1240
    SAM_superfamily; SAM (Sterile alpha motif )
Nucleotide Protein
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