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PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 [ Lonchura striata domestica (Bengalese finch) ]

Gene ID: 110472594, updated on 15-Mar-2024

Summary

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Gene symbol
PIK3R1
Gene description
phosphoinositide-3-kinase regulatory subunit 1
Locus tag
RLOC_00012654
See related
Ensembl:ENSLSDG00000017380
Gene type
protein coding
RefSeq status
MODEL
Organism
Lonchura striata domestica (sub-species: domestica)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Lonchura
Also known as
PIK3R1_0
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
19
Annotation release Status Assembly Chr Location
101 current lonStrDom2 (GCF_005870125.1) Z NC_042595.1 (46871752..46931699)
100 previous assembly LonStrDom1 (GCF_002197715.1) Unplaced Scaffold NW_018656281.1 (4754989..4814938)

Chromosome Z - NC_042595.1Genomic Context describing neighboring genes Neighboring gene CD180 molecule Neighboring gene uncharacterized LOC116184586 Neighboring gene golgi membrane protein 1 Neighboring gene N-alpha-acetyltransferase 35, NatC auxiliary subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in insulin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase regulatory subunit alpha
Names
Phosphatidylinositol 3-kinase regulatory subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lonchura striata domestica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference lonStrDom2 Primary Assembly

Genomic

  1. NC_042595.1 Reference lonStrDom2 Primary Assembly

    Range
    46871752..46931699
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021534414.2 → XP_021390089.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A218VA22
    Related
    ENSLSDP00000024792.1
    Conserved Domains (5) summary
    cd09930
    Location:617 → 720
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:328 → 435
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd11910
    Location:5 → 79
    SH3_PI3K_p85alpha; Src Homology 3 domain of the p85alpha regulatory subunit of Class IA Phosphatidylinositol 3-kinases
    cd12924
    Location:440 → 600
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
    cd04388
    Location:114 → 302
    RhoGAP_p85; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in the p85 isoforms of the regulatory subunit of the class IA PI3K (phosphatidylinositol 3'-kinase). This domain is also called Bcr (breakpoint cluster region protein) ...

  2. XM_021534417.2 → XP_021390092.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X4

    Conserved Domains (3) summary
    cd09930
    Location:296 → 399
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:4 → 114
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12924
    Location:119 → 279
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha

  3. XM_021534416.2 → XP_021390091.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X3

    Related
    ENSLSDP00000024795.1
    Conserved Domains (3) summary
    cd09930
    Location:317 → 420
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:28 → 135
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12924
    Location:140 → 300
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha

  4. XM_021534415.2 → XP_021390090.1  phosphatidylinositol 3-kinase regulatory subunit alpha isoform X2

    Related
    ENSLSDP00000024796.1
    Conserved Domains (3) summary
    cd09930
    Location:347 → 450
    SH2_cSH2_p85_like; C-terminal Src homology 2 (cSH2) domain found in p85
    cd09942
    Location:58 → 165
    SH2_nSH2_p85_like; N-terminal Src homology 2 (nSH2) domain found in p85
    cd12924
    Location:170 → 330
    iSH2_PIK3R1; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunit 1, PIK3R1, also called p85alpha
Nucleotide Protein
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