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DHODH dihydroorotate dehydrogenase (quinone) [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110404156, updated on 15-Mar-2024

Summary

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Gene symbol
DHODH
Gene description
dihydroorotate dehydrogenase (quinone)
See related
Ensembl:ENSNMEG00000005486
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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See DHODH in Genome Data Viewer
Location:
chromosome: 10
Exon count:
8
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 10 NC_034418.1 (19537155..19540768, complement)

Chromosome 10 - NC_034418.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110404162 Neighboring gene DEAH-box helicase 38 Neighboring gene IST1 factor associated with ESCRT-III Neighboring gene zinc finger protein 821 Neighboring gene ataxin 1 like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034418.1 Chromosome 10 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dihydroorotate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' pyrimidine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyrimidine ribonucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydroorotate dehydrogenase (quinone), mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034418.1 Reference NumMel1.0 Primary Assembly

    Range
    19537155..19540768 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021408187.1 → XP_021263862.1  dihydroorotate dehydrogenase (quinone), mitochondrial

    Related
    ENSNMEP00000005233.1, ENSNMET00000008930.1
    Conserved Domains (1) summary
    cd04738
    Location:36 → 365
    DHOD_2_like; Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires ...
Nucleotide Protein
Heading Accession and Version

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