U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 [ Mus pahari (shrew mouse) ]

Gene ID: 110319838, updated on 15-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Arhgef2
Gene description
Rho/Rac guanine nucleotide exchange factor 2
See related
Ensembl:MGP_PahariEiJ_G0026620
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus pahari
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Coelomys
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 4
Exon count:
31
Annotation release Status Assembly Chr Location
101 current PAHARI_EIJ_v1.1 (GCF_900095145.1) 4 NC_034593.1 (79102411..79160766)

Chromosome 4 - NC_034593.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115063808 Neighboring gene signal sequence receptor subunit 2 Neighboring gene small Cajal body-specific RNA 4 Neighboring gene KH domain containing 4, pre-mRNA splicing factor Neighboring gene Ras like without CAAX 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_034593.1 Chromosome 4 Reference PAHARI_EIJ_v1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ruffle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
rho guanine nucleotide exchange factor 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Mus pahari Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PAHARI_EIJ_v1.1

Genomic

  1. NC_034593.1 Reference PAHARI_EIJ_v1.1

    Range
    79102411..79160766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029537334.1 → XP_029393194.1  rho guanine nucleotide exchange factor 2 isoform X2

    Conserved Domains (4) summary
    cd00029
    Location:240 → 285
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:435 → 629
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:998 → 1070
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:669 → 784
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  2. XM_029537333.1 → XP_029393193.1  rho guanine nucleotide exchange factor 2 isoform X1

    Conserved Domains (4) summary
    cd00029
    Location:240 → 285
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:437 → 631
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:1000 → 1072
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:671 → 786
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  3. XM_021195467.2 → XP_021051126.1  rho guanine nucleotide exchange factor 2 isoform X6

    Related
    MGP_PahariEiJ_P0069425, MGP_PahariEiJ_T0069425.1
    Conserved Domains (4) summary
    cd00029
    Location:25 → 70
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:220 → 414
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:783 → 855
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:454 → 569
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  4. XM_029537336.1 → XP_029393196.1  rho guanine nucleotide exchange factor 2 isoform X5

    Related
    MGP_PahariEiJ_P0069424, MGP_PahariEiJ_T0069424.1
    Conserved Domains (4) summary
    cd00029
    Location:25 → 70
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:222 → 416
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:785 → 857
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:456 → 571
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  5. XM_021195464.2 → XP_021051123.1  rho guanine nucleotide exchange factor 2 isoform X3

    Related
    MGP_PahariEiJ_P0069429, MGP_PahariEiJ_T0069429.1
    Conserved Domains (4) summary
    cd00029
    Location:40 → 85
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:237 → 431
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:800 → 872
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:471 → 586
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  6. XM_021195468.2 → XP_021051127.1  rho guanine nucleotide exchange factor 2 isoform X7

    Conserved Domains (4) summary
    cd00029
    Location:13 → 58
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:210 → 404
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:773 → 845
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:444 → 559
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  7. XM_021195469.2 → XP_021051128.1  rho guanine nucleotide exchange factor 2 isoform X8

    Conserved Domains (4) summary
    cd00029
    Location:13 → 58
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:208 → 402
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:771 → 843
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:442 → 557
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain

  8. XM_029537335.1 → XP_029393195.1  rho guanine nucleotide exchange factor 2 isoform X4

    Conserved Domains (4) summary
    cd00029
    Location:32 → 77
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00160
    Location:229 → 423
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    TIGR02680
    Location:792 → 864
    TIGR02680; TIGR02680 family protein
    cd13393
    Location:463 → 578
    PH_ARHGEF2; Rho guanine nucleotide exchange factor 2 Pleckstrin homology (PH) domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.