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Cblc Cbl proto-oncogene C [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110298452, updated on 15-Mar-2024

Summary

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Gene symbol
Cblc
Gene description
Cbl proto-oncogene C
See related
Ensembl:MGP_CAROLIEiJ_G0029309
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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See Cblc in Genome Data Viewer
Location:
chromosome: 7
Exon count:
13
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 7 NC_034576.1 (19077935..19095168, complement)

Chromosome 7 - NC_034576.1Genomic Context describing neighboring genes Neighboring gene nectin cell adhesion molecule 2 Neighboring gene basal cell adhesion molecule (Lutheran blood group) Neighboring gene BCL3 transcription coactivator Neighboring gene CEA cell adhesion molecule 16, tectorial membrane component

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034576.1 Chromosome 7 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL-C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034576.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    19077935..19095168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029479154.1 → XP_029335014.1  E3 ubiquitin-protein ligase CBL-C isoform X1

    UniProtKB/TrEMBL
    A0A6P5Q8M4
    Conserved Domains (4) summary
    cd09920
    Location:225 → 321
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd16710
    Location:344 → 396
    RING-HC_Cbl-c; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-c and similar proteins
    pfam02262
    Location:16 → 141
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:148 → 231
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  2. XM_029479155.1 → XP_029335015.1  E3 ubiquitin-protein ligase CBL-C isoform X2

    UniProtKB/TrEMBL
    A0A6P7RDJ1

  3. XM_021167706.2 → XP_021023365.1  E3 ubiquitin-protein ligase CBL-C isoform X1

    UniProtKB/TrEMBL
    A0A6P5Q8M4
    Related
    MGP_CAROLIEiJ_P0077834, MGP_CAROLIEiJ_T0077834.1
    Conserved Domains (4) summary
    cd09920
    Location:225 → 321
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd16710
    Location:344 → 396
    RING-HC_Cbl-c; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-c and similar proteins
    pfam02262
    Location:16 → 141
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:148 → 231
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  4. XM_021167707.2 → XP_021023366.1  E3 ubiquitin-protein ligase CBL-C isoform X1

    UniProtKB/TrEMBL
    A0A6P5Q8M4
    Related
    MGP_CAROLIEiJ_P0077836, MGP_CAROLIEiJ_T0077836.1
    Conserved Domains (4) summary
    cd09920
    Location:225 → 321
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd16710
    Location:344 → 396
    RING-HC_Cbl-c; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-c and similar proteins
    pfam02262
    Location:16 → 141
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:148 → 231
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein
Heading Accession and Version

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